Evidence map›Paper›PMID 30917851›Full record

ArticleCritical care (London, England)2019

PO

Stefan Boehme, Erik K Hartmann, Thomas Tripp, Serge C Thal, Matthias David, Dietmar Abraham, James E Baumgardner, Klaus Markstaller, Klaus U Klein

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Stefan BoehmeDepartment of Anesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. stefan.boehme@meduniwien.ac.at.ORCID http://orcid.org/0000-0003-3132-2486
Erik K HartmannDepartment of Anesthesiology, Medical Center of the Johannes-Gutenberg University Mainz, Mainz, Germany.
Thomas TrippDepartment of Anesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Serge C ThalDepartment of Anesthesiology, Medical Center of the Johannes-Gutenberg University Mainz, Mainz, Germany.
Matthias DavidDepartment of Anesthesiology, Medical Center of the Johannes-Gutenberg University Mainz, Mainz, Germany.
Dietmar AbrahamCenter for Anatomy and Cell Biology, Division of Cell and Developmental Biology, Medical University of Vienna, Vienna, Austria.
James E BaumgardnerDepartment of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, PA, 15261, USA.
Klaus MarkstallerDepartment of Anesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Klaus U KleinDepartment of Anesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Johannes Gutenberg University Mainz · DEMedical University of Vienna · ATUniversity of Pittsburgh Medical Center · US

Funding

Deutsche Forschungsgemeinschaft Pak 415: Ma 2398/6
6 · The paper itself

Abstract

backgroundMechanical ventilation can lead to ventilator-induced lung injury (VILI). In addition to the well-known mechanical forces of volutrauma, barotrauma, and atelectrauma, non-mechanical mechanisms have recently been discussed as contributing to the pathogenesis of VILI. One such mechanism is oscillations in partial pressure of oxygen (PO

methodsTo separately study the impact of PO

resultsThe LIS showed significantly more severe damage of lung tissue after exposure to PO

conclusionsArtificial mixed-venous PO

Indexed as

AnimalsDisease Models, AnimalEnzyme-Linked Immunosorbent AssayFemaleGermanyOxygenPartial PressurePneumoniaRespiration, ArtificialRespiratory MechanicsSwineVentilator-Induced Lung InjuryOxygenCyclic recruitment and derecruitment of atelectasisInflammationLung injuryPathomechanismPO2 oscillationsVeno-venous extracorporeal membrane oxygenationVentilator-induced lung injury

Identifiers

PMID30917851
PMCPMC6438034
OpenAlexW2937271375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.