Evidence map›Paper›PMID 30917840›Full record

SynthesisCritical care (London, England)2019

A meta-analysis of the resuscitative effects of mechanical and manual chest compression in out-of-hospital cardiac arrest patients.

Ni Zhu, Qi Chen, Zhixia Jiang, Futuan Liao, Bujin Kou, Hui Tang, Manhong Zhou

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Critical care (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04955288 (Research on Key Technologies and System Optimization of Early Warning and Resuscitation of Cardiac Arrest), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04955288 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Research on Key Technologies and System Optimization of Early Warning and Resuscitation of Cardiac Arrest

TypeinterventionalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2021 to 2024Enrolled1,000ConditionsEmergenciesArmsAortic balloon assisted resuscitation, Traditional cardiopulmonary resuscitation, Esophageal cooling, traditional cooling
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ni ZhuEmergency Department, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563003, China.
Qi ChenThe Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zhixia JiangThe Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Futuan LiaoEmergency Department, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563003, China.
Bujin KouEmergency Department, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563003, China.
Hui TangGeneral Practice Department, The Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Manhong ZhouEmergency Department, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563003, China. manahongzhou@126.com.
Zunyi Medical University · CN

Funding

National Natural Science Foundation of China 81460291
6 · The paper itself

Abstract

objectivesTo evaluate the resuscitative effects of mechanical and manual chest compression in patients with out-of-hospital cardiac arrest (OHCA).

methodsAll randomized controlled and cohort studies comparing the effects of mechanical compression and manual compression on cardiopulmonary resuscitation in OHCA patients were retrieved from the Cochrane Library, PubMed, EMBASE, and Ovid databases from the date of their establishment to January 14, 2019. The included outcomes were as follows: the return of spontaneous circulation (ROSC) rate, the rate of survival to hospital admission, the rate of survival to hospital discharge, and neurological function. After evaluating the quality of the studies and summarizing the results, RevMan5.3 software was used for the meta-analysis.

resultsIn total, 15 studies (9 randomized controlled trials and 6 cohort studies) were included. The results of the meta-analysis showed that there were no significant differences in the resuscitative effects of mechanical and manual chest compression in terms of the ROSC rate, the rate of survival to hospital admission and survival to hospital discharge, and neurological function in OHCA patients (ROSC: RCT: OR = 1.12, 95% CI (0.90, 1.39), P = 0.31; cohort study: OR = 1.08, 95% CI (0.85, 1.36), P = 0.54; survival to hospital admission: RCT: OR = 0.95, 95% CI (0.75, 1.20), P = 0.64; cohort study: OR = 0.98 95% CI (0.79, 1.20), P = 0.82; survival to hospital discharge: RCT: OR = 0.87, 95% CI (0.68, 1.10), P = 0.24; cohort study: OR = 0.78, 95% CI (0.53, 1.16), P = 0.22; Cerebral Performance Category (CPC) score: RCT: OR = 0.88, 95% CI (0.64, 1.20), P = 0.41; cohort study: OR = 0.68, 95% CI (0.34, 1.37), P = 0.28). When the mechanical compression group was divided into Lucas and Autopulse subgroups, the Lucas subgroup showed no difference from the manual compression group in ROSC, survival to admission, survival to discharge, and CPC scores; the Autopulse subgroup showed no difference from the manual compression subgroup in ROSC, survival to discharge, and CPC scores.

conclusionThere were no significant differences in resuscitative effects between mechanical and manual chest compression in OHCA patients. To ensure the quality of CPR, we suggest that manual chest compression be applied in the early stage of CPR for OHCA patients, while mechanical compression can be used as part of advanced life support in the late stage.

Indexed as

Cardiopulmonary ResuscitationHumansOut-of-Hospital Cardiac ArrestRandomized Controlled Trials as TopicResuscitationManual chest compressionMechanical chest compressionMeta-analysisOHCAOut-of-hospital cardiac arrest

Identifiers

PMID30917840
PMCPMC6437862
OpenAlexW2939024071

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.