Evidence map›Paper›PMID 30917836›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2019

Kidney transplantation is associated with reduced myocardial fibrosis. A cardiovascular magnetic resonance study with native T1 mapping.

Mariana Moraes Contti, Maurício Fregonesi Barbosa, Alejandra Del Carmen Villanueva Mauricio, Hong Si Nga, Mariana Farina Valiatti, Henrique Mochida Takase, Ariane Moyses Bravin, Luis Gustavo Modelli de Andrade

Abstract read
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. The relationship between native T1 and mortality in patients requiring maintenance haemodialysis, using cardiac magnetic resonance imaging.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  5. Review
  6. TCardiac failure review · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Uraemic Cardiomyopathy: A Review of Current Literature.Clinical Medicine Insights. Cardiology · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariana Moraes ConttiDepartment of Internal Medicine, UNESP, Univ Estadual Paulista, Rubião Jr, s/n, Botucatu/SP, 18.618-970, Brazil.
Maurício Fregonesi BarbosaRadiology Division, UNIFESP, Universidade Federal de São Paulo, São Paulo, Brazil.
Alejandra Del Carmen Villanueva MauricioCardiology Division, UNESP, Univ Estadual Paulista, Botucatu, Brazil.
Hong Si NgaDepartment of Internal Medicine, UNESP, Univ Estadual Paulista, Rubião Jr, s/n, Botucatu/SP, 18.618-970, Brazil.
Mariana Farina ValiattiDepartment of Internal Medicine, UNESP, Univ Estadual Paulista, Rubião Jr, s/n, Botucatu/SP, 18.618-970, Brazil.
Henrique Mochida TakaseDepartment of Internal Medicine, UNESP, Univ Estadual Paulista, Rubião Jr, s/n, Botucatu/SP, 18.618-970, Brazil.
Ariane Moyses BravinDepartment of Internal Medicine, UNESP, Univ Estadual Paulista, Rubião Jr, s/n, Botucatu/SP, 18.618-970, Brazil.
Luis Gustavo Modelli de AndradeDepartment of Internal Medicine, UNESP, Univ Estadual Paulista, Rubião Jr, s/n, Botucatu/SP, 18.618-970, Brazil. gustavomodelli@yahoo.com.br.ORCID 0000-0002-0230-0766

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe measurement of native T1 through cardiovascular magnetic resonance (CMR) is a noninvasive method of assessing myocardial fibrosis without gadolinium contrast. No studies so far have evaluated native T1 after renal transplantation. The primary aim of the current study is to assess changes in the myocardium native T1 6 months after renal transplantation.

methodsWe prospectively evaluated 44 renal transplant patients with 3 T CMR exams: baseline at the beginning of transplantation and at 6 months after transplantation.

resultsThe native T1 time was measured in the midventricular septum and decreased significantly from 1331 ± 52 ms at the baseline to 1298 ± 42 ms 6 months after transplantation (p = 0.001). The patients were split into two groups through a two-step cluster algorithm: In cluster-1 (n = 30) the left ventricular (LV) mass index and the prevalence of diabetes were lower. In cluster-2 (n = 14) the LV mass index and diabetes prevalence were higher. Decrease in native T1 values was significant only in the patients in cluster-1 (p = 0.001).

conclusionsThe native myocardial T1 time decreased significantly 6 months after renal transplant, which may be associated with the regression of the reactive fibrosis. The patients with greater baseline LV mass index and the diabetic group did not reach a significant decrease in T1.

Indexed as

Kidney TransplantationMagnetic Resonance Imaging, CineAdultBrazilCardiomyopathiesDiabetes MellitusFemaleFibrosisHumansMaleMiddle AgedMyocardiumPredictive Value of TestsPrevalenceRenal Insufficiency, ChronicTime FactorsCardiovascular magnetic resonance imagingFibrosisKidney transplantationNative T1

Identifiers

PMID30917836
PMCPMC6437926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.