Evidence map›Paper›PMID 30917747›Full record

ArticleJournal of the American Heart Association2019

Regulation of Intracellular pH is Altered in Cardiac Myocytes of Ovariectomized Rats.

Alejandro Martín Ibañez, María Sofía Espejo, Maite Raquel Zavala, María Celeste Villa-Abrille, Juan Manuel Lofeudo, Ernesto Alejandro Aiello, Verónica Celeste De Giusti

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Left Ventricular Systolic Dysfunction in NBCe1-B/C-Knockout Mice.International journal of molecular sciences · 2024
    Article
  3. Frontiers in cardiovascular medicine · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alejandro Martín Ibañez1 Centro de Investigaciones Cardiovasculares Facultad de Ciencias Médicas Universidad Nacional de La Plata-CONICET La Plata Argentina.
María Sofía Espejo1 Centro de Investigaciones Cardiovasculares Facultad de Ciencias Médicas Universidad Nacional de La Plata-CONICET La Plata Argentina.
Maite Raquel Zavala1 Centro de Investigaciones Cardiovasculares Facultad de Ciencias Médicas Universidad Nacional de La Plata-CONICET La Plata Argentina.
María Celeste Villa-Abrille1 Centro de Investigaciones Cardiovasculares Facultad de Ciencias Médicas Universidad Nacional de La Plata-CONICET La Plata Argentina.
Juan Manuel Lofeudo1 Centro de Investigaciones Cardiovasculares Facultad de Ciencias Médicas Universidad Nacional de La Plata-CONICET La Plata Argentina.
Ernesto Alejandro Aiello1 Centro de Investigaciones Cardiovasculares Facultad de Ciencias Médicas Universidad Nacional de La Plata-CONICET La Plata Argentina.
Verónica Celeste De Giusti1 Centro de Investigaciones Cardiovasculares Facultad de Ciencias Médicas Universidad Nacional de La Plata-CONICET La Plata Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARCentro de Investigaciones Cardiovasculares · ARUniversidad Nacional de La Plata · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background It is well known that after menopause women are exposed to a greater cardiovascular risk, but the intracellular modifications are not properly described. The sodium/proton exchanger (NHE) and the sodium/bicarbonate cotransporter (NBC) regulate the intracellular pH and, indirectly, the intracellular sodium concentration ([Na

Indexed as

OvariectomyAcidosisAnimalsFemaleHydrogen-Ion ConcentrationHypertensionMyocytes, CardiacProto-Oncogene Proteins c-aktRats, WistarSodium-Bicarbonate SymportersSodium-Hydrogen ExchangersProto-Oncogene Proteins c-aktSodium-Bicarbonate SymportersSodium-Hydrogen ExchangersAlcalinizing transporterscardiac myocytecardiac remodelingcardiovascular pathophysiology

Identifiers

PMID30917747
PMCPMC6509710
OpenAlexW2934345236

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.