SynthesisMedicina (Kaunas, Lithuania)2019
How to Manage Impacted Third Molars: Germectomy or Delayed Removal? A Systematic Literature Review.
Synthesis in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Lower Third Molar Germectomy: Timings, Indications, and Clinical and Patient-Reported Outcomes-A Systematic Review and Meta-Analysis.Dentistry journal · 2026Review
- Comparison of Fracture Resistance Based on Ferrule Presence vs Material Type in Maxillary Central Incisor Endocrown Restorations.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Assessing the Management and Evaluation of Impacted Wisdom Teeth in a Dental Teaching Hospital.Dentistry journal · 2025Article
- Relationship between the Status of Third Molars and the Occurrence of Dental and Periodontal Lesions in Adjacent Second Molars in the Polish Population: A Radiological Retrospective Observational Study.Journal of clinical medicine · 2023Article
- Improvement of the Impacted Level of Lower Third Molars After Orthodontic Treatment.International dental journal · 2023Article
- Surgical removal of third molars in a young adult: review of indications and surgical techniques.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2023Article
- Marginal and Para-Marginal Technique in Late Germectomy of Lower Third Molars.Children (Basel, Switzerland) · 2023Article
- Criteria for early diagnosis of third molar agenesis: a retrospective radiographic study.Dental press journal of orthodontics · 2023Article
- Prevalence of mesio-distal dilaceration in patients presenting for initial orthodontic care: A retrospective study.Journal of orthodontic science · 2023Article
- Effect of Craniofacial Morphology on Pharyngeal Airway Volume Measured Using Cone-Beam Computed Tomography (CBCT)-A Retrospective Pilot Study.International journal of environmental research and public health · 2021Article
- The Correlation between Impacted Third Molar and Blood Group.International journal of dentistry · 2021Article
- Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study.International journal of environmental research and public health · 2020Article
- Observational
- Bucco alveolar bone thickness of mandibular impacted third molars with different inclinations: a CBCT study.Surgical and radiologic anatomy : SRA · 2020Article
- 3D Assessment of Endodontic Lesions with a Low-Dose CBCT Protocol.Dentistry journal · 2020Article
- Personalized Dentistry: Approaching a New Way for Diagnosis and Treatment of Oral Diseases.Journal of personalized medicine · 2020Article
- Custom made onlay implants in peek in maxillofacial surgery: a volumetric study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- The Effect of Different Antibiotic Regimens on Bacterial Resistance: A Systematic Review.Antibiotics (Basel, Switzerland) · 2020Review
- Relationship between the Position of Impacted Third Molars and External Root Resorption of Adjacent Second Molars: A Retrospective CBCT Study.Medicina (Kaunas, Lithuania) · 2019Article
- Antibiotic Prophylaxis on Third Molar Extraction: Systematic Review of Recent Data.Antibiotics (Basel, Switzerland) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this systematic review is to evaluate and compare the risks and benefits of germectomy and delayed removal of third molars and develop a patient management algorithm for second molar eruption in syndrome/incompliant patients. MATERIALS AND
methodsA literature search was performed in the following databases; the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Scopus, and Web of Science. Last search was done on July 2nd, 2018 including articles published from the last 18 years. The search aimed to identify all relevant studies written in English language. Gray literature was excluded. Risk of bias was evaluated with specific predetermined criteria. This systematic literature review was reported according to the PRISMA-P statement and was registered in the PROSPERO database with the following protocol ID: 104261.
resultsLiterature search war performed on July 2018 and updated on February 2019. A total of 1610 articles were screened. After abstract screening and discarding duplicates, 86 full-text articles were obtained and subjected to additional evaluation. Four articles were included in the review. Three studies were considered as having a medium risk of bias and one was assessed as at high risk. Due to the heterogeneity of presenting results and a very low number of included studies a quantitative analysis was not possible. Only qualitative analysis was made. Considering the limited number of studies included and the level of risk of bias there is no sufficient evidence to state the benefits of preventive removal of impacted third molars, especially in patients with poor oral hygiene due to intellectual disability. Early germectomy represents an elective approach of pathologic alteration of tooth germ; orthodontic issues meet appropriate indication for a delayed removal.
conclusionsGiven the best evidence-based information regarding patients' medical condition, we highlight the need to provide an ethical-based comprehensive approach in the diagnostic workflow and the assessment of treatment outcome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.