Evidence map›Paper›PMID 30917604›Full record

ReviewGenes2019

The Role of 3' to 5' Reverse RNA Polymerization in tRNA Fidelity and Repair.

Allan W Chen, Malithi I Jayasinghe, Christina Z Chung, Bhalchandra S Rao, Rosan Kenana, Ilka U Heinemann, Jane E Jackman

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. A comparison ofbioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Regreening mechanisms in cucumber: insights from a CsSIG2 mutation affecting chloroplast development.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The life and times of a tRNA.RNA (New York, N.Y.) · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Allan W ChenDepartment of Biochemistry, The University of Western Ontario, 1151 Richmond Street, London, ON N6A 5C1, Canada. achen325@uwo.ca.
Malithi I JayasingheDepartment of Chemistry and Biochemistry, Center for RNA Biology, Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210, USA. jayasinghearachchige.1@osu.edu.
Christina Z ChungDepartment of Biochemistry, The University of Western Ontario, 1151 Richmond Street, London, ON N6A 5C1, Canada. cchung88@uwo.ca.
Bhalchandra S RaoDepartment of Chemistry and Biochemistry, Center for RNA Biology, Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210, USA. brao@arrakistx.com.
Rosan KenanaDepartment of Biochemistry, The University of Western Ontario, 1151 Richmond Street, London, ON N6A 5C1, Canada. rkenana@uwo.ca.
Ilka U HeinemannDepartment of Biochemistry, The University of Western Ontario, 1151 Richmond Street, London, ON N6A 5C1, Canada. ilka.heinemann@uwo.ca.com.
Jane E JackmanDepartment of Chemistry and Biochemistry, Center for RNA Biology, Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210, USA. Jackman.14@osu.edu.
Western University · CAThe Ohio State University · US

Funding

Molecular Mechanism and Biological Function of 3'-5' PolymerasesR01GM087543 · NIGMS · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH · 2010 to 2019
$2.7M
Typhoon FLA9500 Biomedical ImagerS10OD023582 · OD · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH · 2017 to 2017
$144k
NIGMS NIH HHS R01 GM087543NIH HHS S10 OD023582
6 · The paper itself

Abstract

The tRNA

Indexed as

DNA RepairNucleotidyltransferasesRNA, TransferSynthetic BiologyguanylyltransferaseNucleotidyltransferasesRNA, Transferprotein engineeringreverse polymerizationsynthetic biologytRNA editingtRNA repair

Identifiers

PMID30917604
PMCPMC6471195
OpenAlexW2924417616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.