Evidence map›Paper›PMID 30917139›Full record

ArticlePloS one2019

Dog appeasing pheromone prevents the androgen surge and may reduce contact dominance and active submission after stressful interventions in African wild dogs (Lycaon pictus).

Femke Van den Berghe, Monique C J Paris, Zoltan Sarnyai, Bart Vlamings, Robert P Millar, Andre Ganswindt, Alessandro Cozzi, Patrick Pageat, Damien B B P Paris

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. The Brain of the African Wild Dog. VI. The Motor System.The Journal of comparative neurology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Femke Van den BergheGamete and Embryology (GAME) Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.
Monique C J ParisInstitute for Breeding Rare and Endangered African Mammals (IBREAM), Edinburgh, Scotland.
Zoltan SarnyaiLaboratory of Psychiatric Neuroscience, Australian Institute of Tropical Health and Medicine (AITHM) and College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.
Bart VlamingsInstitute for Breeding Rare and Endangered African Mammals (IBREAM), Edinburgh, Scotland.
Robert P MillarInstitute for Breeding Rare and Endangered African Mammals (IBREAM), Edinburgh, Scotland.
Andre GanswindtInstitute for Breeding Rare and Endangered African Mammals (IBREAM), Edinburgh, Scotland.
Alessandro CozziInstitut de Recherche en Sémiochimie et Ethologie Appliquée, Apt, France.
Patrick PageatInstitut de Recherche en Sémiochimie et Ethologie Appliquée, Apt, France.
Damien B B P ParisGamete and Embryology (GAME) Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.
James Cook University · AUInstitut de Recherche en Sémiochimie et Ethologie Appliquée · FROnderstepoort Veterinary Academic Hospital · ZAUniversity of Pretoria · ZAWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endangered African wild dog (AWD; Lycaon pictus) is a highly social canid living in packs with a separate male and female hierarchy. Immobilisation, handling and translocations are acute stressors for AWDs, however such interventions are often needed for species management. In addition, new pack formation or temporary pack separation can lead to an increase in intra-pack aggression. The goal of this double-blinded placebo-controlled study conducted in captive zoo populations was to evaluate whether dog appeasing pheromone (DAP) reduces behavioural stress and faecal glucocorticoid metabolite levels (fGCM) normally associated with pack separation, immobilisation and reintroduction (SIR), and to assess whether this reduces aggressive behaviours and faecal androgen metabolite levels (fAM). Four packs (n = 11 males) were treated with DAP and 4 packs (n = 12 males) were treated with a placebo solution, applied at the end of anaesthesia. Behavioural interactions as well as fGCM and fAM were determined from 3 days before until 4-6 days after SIR. No effect of DAP on fGCM was observed, however, fAM increased after SIR in placebo but not DAP treated animals. Moreover, on the day of reintroduction, DAP treated packs tended to have lower rates of contact-dominance and active-submission behaviour, but higher rates of non-contact dominance behaviour. As these effects could decrease the risk of agonistic interactions, DAP may be a useful tool to help manage new pack formations and temporary pack separation.

Indexed as

Social BehaviorAggressionAndrogensAnimalsAnimals, WildBehavior, AnimalCanidaeFemaleMalePheromonesAndrogensPheromones

Identifiers

PMID30917139
PMCPMC6436694
OpenAlexW2924925288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.