ArticleJournal of neurophysiology2019
V1 microcircuit dynamics: altered signal propagation suggests intracortical origins for adaptation in response to visual repetition.
Article in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 42 citations in OpenAlex.
- Laminar architecture of visual and auditory responses in the supplementary eye field of macaques.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Stimulus Repetition Induces a Two-Stage Learning Process in the Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Delayed Accumulation of Inhibitory Input Explains Gamma Frequency Variation with Changing Contrast in an Inhibition Stabilized Network.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A ubiquitous spectrolaminar motif of local field potential power across the primate cortex.Nature neuroscience · 2024Article
- Adaptation of the inferior temporal neurons and efficient visual processing.Frontiers in behavioral neuroscience · 2024Review
- Feedforward attentional selection in sensory cortex.Nature communications · 2023Article
- A role for ocular dominance in binocular integration.Current biology : CB · 2023Article
- Does V1 response suppression initiate binocular rivalry?iScience · 2023Article
- Rapid adaptation of primate LGN neurons to drifting grating stimulation.Journal of neurophysiology · 2023Article
- Independent repetition suppression in macaque area V2 and inferotemporal cortex.Journal of neurophysiology · 2022Article
- Resolving the mesoscopic missing link: Biophysical modeling of EEG from cortical columns in primates.NeuroImage · 2022Article
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- Pop-out search instigates beta-gated feature selectivity enhancement across V4 layers.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- History Modulates Early Sensory Processing of Salient Distractors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Neural mechanism of priming in visual search.Attention, perception & psychophysics · 2021Review
- Learning poly-synaptic paths with traveling waves.PLoS computational biology · 2021Article
- Layer and rhythm specificity for predictive routing.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
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- Layer-Specific Contributions to Imagined and Executed Hand Movements in Human Primary Motor Cortex.Current biology : CB · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Repetitive visual stimulation profoundly changes sensory processing in the primary visual cortex (V1). We show how the associated adaptive changes are linked to an altered flow of synaptic activation across the V1 laminar microcircuit. Using repeated visual stimulation, we recorded layer-specific responses in V1 of two fixating monkeys. We found that repetition-related spiking suppression was most pronounced outside granular V1 layers that receive the main retinogeniculate input. This repetition-related response suppression was robust to alternating stimuli between the eyes, in line with the notion that repetition-related adaptation is predominantly of cortical origin. Most importantly, current source density (CSD) analysis, which provides an estimate of local net depolarization, revealed that synaptic processing during repeated stimulation was most profoundly affected within supragranular layers, which harbor the bulk of cortico-cortical connections. Direct comparison of the temporal evolution of laminar CSD and spiking activity showed that stimulus repetition first affected supragranular synaptic currents, which translated into a reduction of stimulus-evoked spiking across layers. Together, these results suggest that repetition induces an altered state of intracortical processing that underpins visual adaptation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.