Evidence map›Paper›PMID 30917014›Full record

ArticleAIDS education and prevention : official publication of the International Society for AIDS Education2019

Designing an Individually Tailored Multilevel Intervention to Increase Engagement in HIV and Substance Use Treatment Among People Who Inject Drugs With HIV: HPTN 074.

Kathryn E Lancaster, William C Miller, Tetiana Kiriazova, Riza Sarasvita, Quynh Bui, Tran Viet Ha, Kostyantyn Dumchev, Hepa Susami, Erica L Hamilton, Scott Rose and 5 more

Abstract read
In one paragraph

Article in AIDS education and prevention : official publication of the International Society for AIDS Education, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kathryn E LancasterCollege of Public Health, The Ohio State University, Columbus, Ohio.
William C MillerCollege of Public Health, The Ohio State University, Columbus, Ohio.
Tetiana KiriazovaUkrainian Institute on Public Health Policy, Kyiv, Ukraine.
Riza SarasvitaNational Narcotics Board, Jakarta, Indonesia.
Quynh BuiUNC Project Vietnam, Hanoi, Vietnam.
Tran Viet HaUNC Project Vietnam, Hanoi, Vietnam.
Kostyantyn DumchevUkrainian Institute on Public Health Policy, Kyiv, Ukraine.
Hepa SusamiAbhipraya Foundation and Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Erica L HamiltonScience Facilitation Department, Durham, North Carolina.
Scott RoseScience Facilitation Department, Durham, North Carolina.
Rebecca B HershowDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina.
Vivian F GoDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina.
David MetzgerPerelman School of Medicine, University of Pennsylvania and the Treatment Research Institute, Philadelphia, Pennsylvania.
Irving F HoffmanDivision of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill.
Carl A LatkinBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Karine Dube · 2013 to 2026
$23.5M
NIAID NIH HHS P30 AI050410NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619NIMH NIH HHS P30 MH097488
6 · The paper itself

Abstract

People who inject drugs (PWID) face barriers to engagement in antiretro-viral treatment (ART) and medication-assisted treatment (MAT). We detail the design, rapid preparation and adaptation, and systematic implementation of a flexible, individually tailored intervention for PWID in multiple settings: Indonesia, Ukraine, and Vietnam. HPTN 074 integrated systems navigation and counseling to facilitate entry and adherence to ART and MAT. Site-level guidance on the intervention involved in-depth interviews (IDIs) among PWID and their supporters and site-specific document review. IDIs emphasized ART misinformation and importance of social support for adherence. The document review revealed differences in health care system barriers, requiring an intervention that was flexible and tailored enough to address key outcomes. Implementation included regular debriefs for iterative adaptations based on participants' needs, including booster counseling sessions and subsidizing pre-ART testing. HPTN 074 provides a unique framework implementing a flexible and scalable intervention to improve ART and MAT outcomes among PWID across multiple settings.

Indexed as

AdultAnti-Retroviral AgentsCounselingDrug UsersFemaleHIV InfectionsHumansIndonesiaMaleMedication AdherencePatient Acceptance of Health CarePatient-Centered CareSubstance Abuse, IntravenousUkraineVietnamAnti-Retroviral AgentsARTHIVinjection drug usemedication-assisted treatmentsubstance use

Identifiers

PMID30917014
PMCPMC6594165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.