Evidence map›Paper›PMID 30917003›Full record

ReviewAnnual review of biochemistry2019

Glycoengineering of Antibodies for Modulating Functions.

Lai-Xi Wang, Xin Tong, Chao Li, John P Giddens, Tiezheng Li

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 132 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Selective fluorination of Fc glycans enhances antibody-mediated effector functions.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. JACS Au · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Exploring glycoform-dependent dynamic modulations in human immunoglobulin G via computational and experimental approaches.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Glycoengineering in antigen-specific immunotherapies.Current opinion in chemical biology · 2024
    Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lai-Xi WangDepartment of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA; email: wang518@umd.edu , xtong1@umd.edu , chaoli@umd.edu , johnpgiddens@gmail.com , kevintiezhengli@gmail.com.
Xin TongDepartment of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA; email: wang518@umd.edu , xtong1@umd.edu , chaoli@umd.edu , johnpgiddens@gmail.com , kevintiezhengli@gmail.com.
Chao LiDepartment of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA; email: wang518@umd.edu , xtong1@umd.edu , chaoli@umd.edu , johnpgiddens@gmail.com , kevintiezhengli@gmail.com.
John P GiddensDepartment of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA; email: wang518@umd.edu , xtong1@umd.edu , chaoli@umd.edu , johnpgiddens@gmail.com , kevintiezhengli@gmail.com.
Tiezheng LiDepartment of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA; email: wang518@umd.edu , xtong1@umd.edu , chaoli@umd.edu , johnpgiddens@gmail.com , kevintiezhengli@gmail.com.
University of Maryland, College Park · US

Funding

Covergent Chemoenzymatic Synthesis of Glycopeptides and GlycoproteinsR01GM080374 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI WANG, LAI-XI · 2007 to 2021
$3.9M
Synthesis and Function of Antibody Fc Domain GlycoformsR01GM096973 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI WANG, LAI-XI · 2011 to 2020
$2.4M
NIGMS NIH HHS R01 GM080374NIGMS NIH HHS R01 GM096973
6 · The paper itself

Abstract

Antibodies are immunoglobulins that play essential roles in immune systems. All antibodies are glycoproteins that carry at least one or more conserved

Indexed as

AnimalsAntibodiesGlycoproteinsGlycosylationHumansProtein EngineeringAntibodiesGlycoproteinsantibodyantibody–drug conjugatechemoenzymaticglycoengineeringglycosylation

Identifiers

PMID30917003
PMCPMC6923169
OpenAlexW2923750883

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.