Evidence map›Paper›PMID 30916989›Full record

ArticleAmerican journal of respiratory cell and molecular biology2019

Sarmila Basnet, Yury A Bochkov, Rebecca A Brockman-Schneider, Ine Kuipers, Scott W Aesif, Daniel J Jackson, Robert F Lemanske, Carol Ober, Ann C Palmenberg, James E Gern

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Treatment by biomarker-informed endotype vs guideline care in children with difficult-to-treat asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The rhinovirus puzzle: Linking virus and host factors to childhood asthma.The Journal of allergy and clinical immunology · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The usual suspects: Respiratory syncytial virus and rhinovirus drive asthma development and exacerbation.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Review
  16. Genetic Susceptibility to Acute Viral Bronchiolitis.The Journal of infectious diseases · 2025
    Article
  17. Article
  18. Article
  19. Interplay between respiratory viruses and cilia in the airways.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sarmila BasnetDepartment of Pediatrics.
Yury A BochkovDepartment of Pediatrics.
Rebecca A Brockman-SchneiderDepartment of Pediatrics.
Ine KuipersDepartment of Pediatrics.
Scott W AesifDepartment of Pathology and Laboratory Medicine, and.
Daniel J JacksonDepartment of Pediatrics.
Robert F LemanskeDepartment of Pediatrics.
Carol OberDepartment of Human Genetics, University of Chicago, Chicago, Illinois.
Ann C PalmenbergInstitute of Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin; and.
James E GernDepartment of Pediatrics.
Emory University Hospital · USUniversity of Chicago · USUniversity of Wisconsin–Madison · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Virus-Bacterial Interactions and Exacerba of AsthmaP01HL070831 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BOCHKOV, YURY A · 2002 to 2017
$31.3M
Wisconsin Infant Study Cohort (WISC)U19AI104317 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern, CHRISTINE Marie SEROOGY · 2013 to 2026
$22.5M
NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373NHLBI NIH HHS P01 HL070831NIAID NIH HHS U19 AI104317
6 · The paper itself

Abstract

CDHR3 (cadherin-related family member 3) is a transmembrane protein that is highly expressed in airway epithelia and the only known receptor for rhinovirus C (RV-C). A

Indexed as

Polymorphism, Single NucleotideAllelesAsthmaBronchiCadherin Related ProteinsCadherinsCiliaEpithelial CellsGenetic Predisposition to DiseaseGenotypeHumansMembrane ProteinsPicornaviridae InfectionsRespiratory MucosaRhinovirusSubcellular FractionsCadherin Related ProteinsCadherinsCDHR3 protein, humanMembrane Proteinsbronchial epitheliumcadherin-related family member 3ciliageneticsrhinovirus

Identifiers

PMID30916989
PMCPMC6775945
OpenAlexW2923320946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.