ReviewBritish journal of anaesthesia2019
The prescription opioid crisis: role of the anaesthesiologist in reducing opioid use and misuse.
Review in British journal of anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 50 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy: A Randomized Placebo-Controlled Trial
Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Transversus Abdominus Plane Block for Laparoscopic Sleeve Gastrectomy-A Systematic Review and Meta-analysis of Randomized Clinical Trials.Obesity surgery · 2025Pooled it
- Pooled it
- The effect of ultrasound-guided erector spinae plane block on postsurgical pain: a meta-analysis of randomized controlled trials.BMC anesthesiology · 2020Pooled it
- Opioid administration guided by Surgical Pleth Index in patients with a combination of general and regional anaesthesia during trauma and orthopaedic surgery: a double-blind, randomised controlled trial.Journal of clinical monitoring and computing · 2026Trial
- Opioid-based versus opioid-sparing patient-controlled analgesia using ketorolac and nefopam after total knee arthroplasty: a randomized, double-blind, non-inferiority trial.Korean journal of anesthesiology · 2026Trial
- Feasibility of Prospectively Comparing Opioid Analgesia With Opioid-Free Analgesia After Outpatient General Surgery: A Pilot Randomized Clinical Trial.JAMA network open · 2022Trial
- Opioid-Sparing Analgesia Impacts the Perioperative Anesthetic Management in Major Abdominal Surgery.Medicina (Kaunas, Lithuania) · 2022Trial
- Neutrophil-to-Lymphocyte Ratio as an Indicator of Opioid-Induced Immunosuppression After Thoracoscopic Surgery: A Randomized Controlled Trial.Journal of pain research · 2022Trial
- Efficacy and Safety of Opioid Analgesia in Acute Abdominal Presentations: A Systematic Review.Cureus · 2026Review
- The transitional pain service: a narrative review on the approach to managing chronic post-surgical pain.Journal of anesthesia · 2026Review
- Opioid Free Anesthesia in Arthroscopic Knee Surgery: A Feasible Approach to Patient Care.HCA healthcare journal of medicine · 2026Article
- Review
- Peripheral nerve blocks for perioperative analgesia: das Kind mit dem Bade ausschütten...throwing the baby out with the bathwater?British journal of anaesthesia · 2025Article
- Balancing benefit and risk: clinical considerations in the use of acetaminophen, non-steroidal anti-inflammatory drugs, and dexamethasone for perioperative multimodal analgesia.The Korean journal of pain · 2025Review
- Trends in non-opioid analgesic use following major abdominal surgery: a retrospective single-center cohort study.The Korean journal of pain · 2025Article
- Persistent Improvement in Opioid Perceptions and Prescribing for Cancer Surgery: 5-Year Follow-Up.Advances in cancer education and quality improvement · 2025Article
- Reducing Postoperative Opioid Use: A Comparison of Open Versus Ultrasound-Guided Regional Anesthesia for Patients Undergoing Open Pancreatoduodenectomy.Journal of surgical oncology · 2025Article
- Assessing medical students' beliefs about the opioid crisis and their post-graduation plans: a cross-sectional study.BMC medical education · 2025Article
- Analysis of User-Generated Posts on Social Media of Adjuvant Analgesics: A Machine Learning Study.International journal of medical sciences · 2025Article
- Overview and Prospects of the Clinical Application of Oliceridine.Drug design, development and therapy · 2025Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Reports of strategies to prevent and treat the opioid epidemic are growing. Significant attention has been paid to the benefits of opioid addiction research, clinical prescribing, and public policy initiatives in curbing the epidemic. However, the role of the anaesthesiologist in minimising opioid use and misuse remains underexplored. For many patients with an opioid use disorder, the perioperative period represents the source of initial exposure. As perioperative physicians, anaesthesiologists are in the unique position to manage pain effectively while simultaneously decreasing opioid consumption. Multiple opportunities exist for anaesthesiologists to minimise opioid exposure and prevent subsequent persistent opioid use. We present a global strategy for decreasing perioperative opioid use and misuse among surgical patients. A historical perspective of the opioid epidemic is presented, together with an analysis of opioid supply and demand forces. We then present specific temporal strategies for opioid use reduction in the perioperative period. We emphasise the importance of preoperative identification of patients at risk for long-term opioid use and misuse, review the evidence supporting the opioid sparing capacity of individual multimodal analgesic agents, and discuss the benefits of regional anaesthesia for minimising opioid consumption. We describe postoperative and post-discharge tools, including effective multimodal analgesia and the role of a transitional pain service. Finally, we offer general institutional strategies that can be led by anaesthesiologists, identify gaps in knowledge, and offer directions for future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.