Evidence map›Paper›PMID 30915597›Full record

ArticleWorld journal of microbiology & biotechnology2019

RNA-seq transcriptomic analysis of green tea polyphenols regulation of differently expressed genes in Saccharomyces cerevisiae under ethanol stress.

Lu Cheng, Xin Zhang, Xiaojie Zheng, Zufang Wu, Peifang Weng

Abstract read
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In one paragraph

Article in World journal of microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. RewiringMetabolic engineering communications · 2024
    Article
  3. Integrative Analysis of the Ethanol Tolerance ofInternational journal of molecular sciences · 2023
    Article
  4. Adaptive mechanism ofFood science & nutrition · 2022
    Article
  5. Article
  6. Article
  7. Protective Effects of Melatonin onAntioxidants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lu ChengDepartment of Food Science, Rutgers University, New Brunswick, NJ, 08901, USA.
Xin ZhangDepartment of Food Science and Engineering, Ningbo University, Ningbo, 315211, People's Republic of China.
Xiaojie ZhengDepartment of Agriculture and Biotechnology, Wenzhou Vocational College of Science and Technology, Wenzhou, 325006, People's Republic of China.
Zufang WuDepartment of Food Science and Engineering, Ningbo University, Ningbo, 315211, People's Republic of China.
Peifang WengDepartment of Food Science and Engineering, Ningbo University, Ningbo, 315211, People's Republic of China. pdfelement@163.com.ORCID http://orcid.org/0000-0001-9704-172X
Ningbo University · CNRutgers, The State University of New Jersey · USWenzhou Vocational College of Science and Technology · CN

Funding

Key Research and Development Project of Zhejiang Province 2017C02039Key Research and Development Project of Zhejiang Province 2018C02047
6 · The paper itself

Abstract

Saccharomyces cerevisiae has been widely used to produce alcoholic beverages and bio-fuels; however, its performance is remarkably compromised by the increased ethanol concentration during the fermentation process. In this study, RNA-sequence analysis was used to investigate the protective effect of green tea polyphenols (GTP) on S. cerevisiae cells from ethanol-induced damage. GO and KEGG analysis showed that to deal with the stress of ethanol, large amounts of genes related to cell wall, cell membrane, basic metabolism and redox regulation were significantly differentially expressed (P < 0.05), while these undesired changes could be partly relieved by administration of GTP, suggesting its potential to enhance the ethanol tolerance of S. cerevisiae. The present study provided a global view of the transcriptomic changes of S. cerevisiae in response to the accumulation of ethanol and the treatment of GTP, which might deepen our understanding about S. cerevisiae and the fermentation process, and thus benefit the development of the bioethanol production industry.

Indexed as

Stress, PhysiologicalTranscriptomeCell MembraneCell WallDrug ToleranceEthanolFermentationGene Expression ProfilingGene Expression Regulation, FungalGuanosine TriphosphateIndustrial MicrobiologyPlant ExtractsPolyphenolsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence Analysis, RNAEthanolGuanosine TriphosphatePlant ExtractsPolyphenolsSaccharomyces cerevisiae ProteinsTeaEthanol stressGreen tea polyphenolsSaccharomyces cerevisiaeTranscriptome

Identifiers

PMID30915597
OpenAlexW2922700647

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.