Observational studyEuropean radiology2019
Preoperative assessment of parietal pleural invasion/adhesion of subpleural lung cancer: advantage of software-assisted analysis of 4-dimensional dynamic-ventilation computed tomography.
Observational study in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Strain analysis based on dynamic ventilation computed tomography in fibrotic interstitial lung disease and its correlation with pulmonary function tests.Quantitative imaging in medicine and surgery · 2026Article
- Research progress on imaging prediction of pleural adhesion: a narrative review.Journal of thoracic disease · 2026Review
- Diagnostic utility of chest wall vessel involvement sign on ultra-high-resolution CT for primary lung cancer infiltrating the chest wall.European radiology · 2025Article
- Chest wall resections for non-small cell lung cancer: a literature review.Journal of thoracic disease · 2024Review
- Evaluation of parietal pleural adhesion and invasion in subpleural lung cancer: value of B-mode ultrasound and contrast-enhanced ultrasound.Quantitative imaging in medicine and surgery · 2024Article
- Right main pulmonary artery distensibility on dynamic ventilation CT and its association with respiratory function.European radiology experimental · 2024Article
- Utilization of intraoperative indocyanine green fluorescence imaging to identify vascular anatomy in severe pleural adhesions in uniportal video-assisted thoracoscopic surgery: a case report.Translational cancer research · 2023Article
- Area-Detector Computed Tomography for Pulmonary Functional Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Preoperative assessment of pleural adhesions in patients with lung cancer based on quantitative motion analysis with dynamic chest radiography: A retrospective study.Journal of applied clinical medical physics · 2023Article
- Correlation between pleural tags on CT and visceral pleural invasion of peripheral lung cancer that does not appear touching the pleural surface.European radiology · 2021Article
- Preoperative prediction of the localization of a solitary fibrous tumor using four-dimensional computed tomography: a case report.Journal of surgical case reports · 2021Article
- Pearls and pitfalls in lung cancer staging.BJR open · 2020Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate the accuracy of four-dimensional (4D) dynamic-ventilation computed tomography (CT) scanning coupled with our novel image analysis software to diagnose parietal pleural invasion/adhesion of peripheral (subpleural) lung cancer.
methodsEighteen patients with subpleural lung cancer underwent both 4D dynamic-ventilation CT during free breathing and conventional (static) chest CT during preoperative assessment. The absence of parietal pleural invasion/adhesion was surgically confirmed in 13 patients, while the presence of parietal pleural invasion/adhesion was confirmed in 5 patients. Two chest radiologists, who were blinded to patient status, cooperatively evaluated the presence of pleural invasion/adhesion using two different imaging modalities: (i) conventional high-resolution CT images, reconstructed in the axial, coronal, and sagittal directions, and (ii) 4D dynamic-ventilation CT images combined with a color map created by image analysis software to visualize movement differences between the lung surface and chest wall. Parameters of diagnostic accuracy were assessed, including a receiver operating characteristic analysis.
resultsSoftware-assisted 4D dynamic-ventilation CT images achieved perfect diagnostic accuracy for pleural invasion/adhesion (sensitivity, 100%; specificity, 100%; area under the curve [AUC], 1.000) compared to conventional chest CT (sensitivity, 60%; specificity, 77%; AUC, 0.846).
conclusionSoftware-assisted 4D dynamic-ventilation CT can be considered as a novel imaging approach for accurate preoperative analysis of pleural invasion/adhesion of peripheral lung cancer. KEY POINTS: • 4D dynamic-ventilation CT can correctly assess parietal pleural invasion/adhesion of peripheral lung cancer. • A unique color map clearly demonstrates parietal pleural invasion/adhesion. • Our technique can be expanded to diagnose "benign" pleural adhesions for safer thoracoscopic surgery.
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