Evidence map›Paper›PMID 30915541›Full record

ArticleInternational journal of colorectal disease2019

Oncological outcome of peripartum colorectal carcinoma-a single-center experience.

Fabian Grass, Blake A Spindler, Nimesh D Naik, Cornelius A Thiels, Eric J Dozois, David W Larson, Kellie L Mathis

Abstract read
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In one paragraph

Article in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Multidisciplinary consensus on cancer management during pregnancy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  6. Colorectal cancer in the setting of pregnancy and familial risk.International journal of colorectal disease · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fabian GrassDivision of Colon and Rectal Surgery, Assistant Professor of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.ORCID http://orcid.org/0000-0001-9884-2879
Blake A SpindlerDivision of Colon and Rectal Surgery, Assistant Professor of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Nimesh D NaikDivision of Colon and Rectal Surgery, Assistant Professor of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Cornelius A ThielsDivision of Colon and Rectal Surgery, Assistant Professor of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Eric J Dozois
David W LarsonDivision of Colon and Rectal Surgery, Assistant Professor of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Kellie L MathisDivision of Colon and Rectal Surgery, Assistant Professor of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Mathis.kellie@mayo.edu.
Mayo Clinic · USColon and Rectal Surgery Associates · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to analyze disease presentation, management, and oncological outcomes of patients diagnosed with peripartum colorectal cancer (CRC).

methodsRetrospective cohort study of all consecutive women of childbearing age (18-45 years) between 2002 and 2014 diagnosed with CRC adenocarcinoma at a tertiary academic institution. Patients who experienced pregnancy within 12 months of their diagnosis (peripartum period, group 1) were compared to the remaining patients of the cohort (group 2). Overall survival (OS) was compared between the two groups through Kaplan-Meier estimates.

resultsOut of 555 consecutive women with a mean age of 37.8 + 6 years, 31 (5.6%) were diagnosed with CRC in the peripartum period. Of these, all patients were symptomatic during pregnancy due to bleeding, abdominal pain, or constipation; however, only 11 CRC (35.5%) were diagnosed during pregnancy, 1 (3.2%) during C section, and the remaining (61.3%) postpartum. TNM stage at presentation was I in 6 patients (19.4%), II in 4 patients (13.9%), III in 8 patients (25.8%), and IV in 13 patients (41.9%). Surgical resection was performed in 23 patients (74.2%): 2 while pregnant, 2 at the time of C section, and the remainder postpartum. Across all stages, OS was 95% at 1 year and 62% at 5 years and did not differ between the two comparative groups (p = 0.16).

conclusionsA suspicious attitude towards cancer-related symptoms during pregnancy is crucial to prevent delayed evaluation for CRC.

Indexed as

AdultColorectal NeoplasmsFemaleHumansKaplan-Meier EstimateMultivariate AnalysisPeripartum PeriodTreatment OutcomeColorectal carcinomaOutcomePregnancySurvival

Identifiers

PMID30915541
OpenAlexW2924558955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.