Trial reportBioMed research international2019
The Effectiveness of Ultrasound-Guided Steroid Injection Combined with Miniscalpel-Needle Release in the Treatment of Carpal Tunnel Syndrome vs. Steroid Injection Alone: A Randomized Controlled Study.
Trial report in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- [Carpal tunnel release with ultrasound guidance : Efficacy and safety].Orthopadie (Heidelberg, Germany) · 2026Pooled it
- Surgical versus non-surgical treatment for carpal tunnel syndrome.The Cochrane database of systematic reviews · 2024Pooled it
- Diagnostic criteria and outcome measures in randomized clinical trials on carpal tunnel syndrome: a systematic review.Sao Paulo medical journal = Revista paulista de medicina · 2023Pooled it
- A Mechanism-Based Classification and Review of Endoscopic and Ultrasound-Guided Carpal Tunnel Release.Journal of clinical medicine · 2026Review
- Article
- Prospective evaluation of a novel device for ultrasound-guided percutaneous treatment of carpal tunnel and trigger finger disease. Efficacy and safety of sono-instruments®.Journal of ultrasound · 2024Article
- Ultrasound guided procedures in the musculoskeletal system: a narrative review with illustrative examples.Quantitative imaging in medicine and surgery · 2024Review
- Analysis of Research Trends in Ultrasound-Guided Acupuncture and Dry-Needling: A Scoping Review.Journal of clinical medicine · 2024Article
- Ultrasound-Guided Interventions for Carpal Tunnel Syndrome: A Systematic Review and Meta-Analyses.Diagnostics (Basel, Switzerland) · 2023Review
- The outcomes of carpal tunnel decompression based on electro-diagnostic approaches and clinical symptoms in patients suffering from carpal tunnel syndrome (CTS).Journal of family medicine and primary care · 2022Article
- Carpal tunnel syndrome conservative treatment: a literature review.Postepy psychiatrii neurologii · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCarpal tunnel syndrome (CTS) is one of the most common nerve entrapment syndromes, which has a serious impact on patients' work and life. The most effective conservative treatment is steroid injection but its long-term efficacy is still not satisfactory. The aim of this study was to evaluate the effectiveness of steroid injection combined with miniscalpel-needle (MSN) release for treatment of CTS under ultrasound guidance versus steroid injection alone. We hypothesized that combined therapy could be more beneficial.
methodsFifty-one patients with CTS were randomly allocated into two groups, namely, steroid injection combined with MSN release group and steroid injection group. The therapeutic effectiveness was evaluated using Boston Carpal Tunnel Questionnaire (BCTQ), cross-sectional area (CSA) of the median nerve, and four electrophysiological parameters, including distal motor latency (DML), compound muscle action potential (CMAP), sensory nerve action potential (SNAP), and sensory nerve conduction velocity (SNCV) at baseline, 4 and 12 weeks after treatment.
resultsCompared with baseline, all the parameters in both groups showed statistically significant improvement at week 4 and week 12 follow-up, respectively (
conclusionsThe effectiveness of steroid injection combined with MSN release for CTS is superior to that of steroid injection alone, which may have important implications for future clinical practice. This Chinese clinical trial is registered with ChiCTR1800014530.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.