Evidence map›Paper›PMID 30915280›Full record

ArticleFrontiers in cellular and infection microbiology2019

Comparison of Subgingival and Buccal Mucosa Microbiome in Chronic and Aggressive Periodontitis: A Pilot Study.

Yiping Wei, Meng Shi, Min Zhen, Cui Wang, Wenjie Hu, Yong Nie, Xiaolei Wu

Open access · goldAbstract readComparative Study
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. The role of salivary metabolomics in chronic periodontitis: bridging oral and systemic diseases.Metabolomics : Official journal of the Metabolomic Society · 2025
    Review
  5. Review
  6. Journal of oral microbiology · 2025
    Article
  7. Review
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  9. Review
  10. Review
  11. Article
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  14. Article
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  19. The Treatment Efficiency and Microbiota Analysis ofInternational journal of molecular sciences · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yiping WeiNational Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Department of Periodontology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Beijing, China.
Meng ShiNational Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Department of Periodontology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Beijing, China.
Min ZhenNational Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Department of Periodontology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Beijing, China.
Cui WangNational Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Department of Periodontology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Beijing, China.
Wenjie HuNational Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Department of Periodontology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Beijing, China.
Yong NieLaboratory of Environmental Microbiology, Department of Energy and Resources Engineering, College of Engineering, Peking University, Beijing, China.
Xiaolei WuLaboratory of Environmental Microbiology, Department of Energy and Resources Engineering, College of Engineering, Peking University, Beijing, China.
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal microorganisms not only colonize subgingival pockets, but also are detected on various mucous membranes in patients with periodontitis. The object of this pilot study was, using the next-generation sequencing of 16S RNA gene, to characterize the microbiota in two oral habitats (buccal mucosas and subgingival pockets) in patients with different forms of periodontitis. Thirty-two buccal swab samples and 113 subgingival samples were obtained from eleven subjects with chronic periodontitis (ChP), twelve subjects with aggressive periodontitis (AgP), and nine periodontally healthy individuals (HP). Using Miseq Sequencing of 16S rRNA gene, we found that the subgingival and buccal mucosa microbiome of ChP and AgP patients both differed from HP. Meanwhile,

Indexed as

MicrobiotaAdultAggressive PeriodontitisChronic DiseaseCluster AnalysisDNA, BacterialDNA, RibosomalFemaleGingivaHumansMaleMetagenomicsMouth MucosaPhylogenyPilot ProjectsRNA, Ribosomal, 16SDNA, BacterialDNA, RibosomalRNA, Ribosomal, 16S16S sequencingaggressive periodontitisbuccal mucosa microbiomechronic periodontitissubgingival microbiome

Identifiers

PMID30915280
PMCPMC6421285
OpenAlexW2922164353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.