Evidence map›Paper›PMID 30915240›Full record

ArticleInternational journal of breast cancer2019

Extreme Oncoplastic Surgery for Multifocal/Multicentric and Locally Advanced Breast Cancer.

Chaitanyanand B Koppiker, Aijaz Ul Noor, Santosh Dixit, Laleh Busheri, Gautam Sharan, Upendra Dhar, Hari Kiran Allampati, Smeeta Nare

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In one paragraph

Article in International journal of breast cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Breast conservation surgery & oncoplasty in India - Current scenario.The Indian journal of medical research · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Chaitanyanand B KoppikerOrchids Breast Health Clinic, Prashanti Cancer Care Mission, 1&2, Kapilavastu, Senapati Bapat Road, Pune, Maharashtra 411016, India.ORCID 0000-0002-1363-274X
Aijaz Ul NoorOrchids Breast Health Clinic, Prashanti Cancer Care Mission, 1&2, Kapilavastu, Senapati Bapat Road, Pune, Maharashtra 411016, India.
Santosh DixitOrchids Breast Health Clinic, Prashanti Cancer Care Mission, 1&2, Kapilavastu, Senapati Bapat Road, Pune, Maharashtra 411016, India.
Laleh BusheriOrchids Breast Health Clinic, Prashanti Cancer Care Mission, 1&2, Kapilavastu, Senapati Bapat Road, Pune, Maharashtra 411016, India.
Gautam SharanDepartment of Radiation Oncology, Inlaks and Budhrani Hospital, Pune 411001, India.
Upendra DharOrchids Breast Health Clinic, Prashanti Cancer Care Mission, 1&2, Kapilavastu, Senapati Bapat Road, Pune, Maharashtra 411016, India.
Hari Kiran AllampatiRuby Hall Clinic, Pune, Maharashtra 411040, India.
Smeeta NareOrchids Breast Health Clinic, Prashanti Cancer Care Mission, 1&2, Kapilavastu, Senapati Bapat Road, Pune, Maharashtra 411016, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBreast conserving surgery (BCS) followed by radiation therapy (RT) has become the preferred alternative to mastectomy for patients with early stage breast cancer (BC). Randomized trials have confirmed equivalent locoregional control and overall survival for BCS and mastectomy. Extreme Oncoplasty (EO) extends the indications of BCS for patients who would otherwise require mastectomy, ensuring better aesthetic outcomes and oncological safety.

methodsBC patients with multifocal/multicentric (MF/MC) tumors, extensive DCIS, or large tumor >50mm underwent EO at our breast unit. Therapeutic reduction mammaplasty (TRM) with wise pattern preoperative markings and dual pedicle technique involving parenchymal rearrangement was used for oncoplastic reconstructions in majority of the cases followed by RT. Patient reported outcome measures (PROMs) were assessed using the validated Breast-Q questionnaire.

resultsOf the 39 patients in the study, 36 had unilateral and 3 had bilateral BC. Mean age was 47.2 years. Median tumor size was 75mm. 17 (43.6%) patients received NACT; none achieved a complete clinical response. 28 (71.8%) patients were administered to adjuvant chemotherapy. 33(84.6%) patients received RT to the breast with a median dose of 50Gy in 28 fractions and a boost dose of 10Gy in 5 fractions to the tumor bed. No major complications or local recurrences were observed. Excellent Breast-Q scores were observed in patients undergoing EO after 12 months of follow-up.

conclusionEO followed by RT results in acceptable local-regional control, low rate of complications, and high patient satisfaction. In selected patients, EO could provide a safe alternative for breast conservation surgery instead of mastectomy.

Identifiers

PMID30915240
PMCPMC6402217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.