Evidence map›Paper›PMID 30915237›Full record

ArticleJournal of ophthalmology2019

The Relationship between Carotid Intima-Media Thickness and Ocular Circulation in Type-2 Diabetes.

Kohei Ichinohasama, Hiroshi Kunikata, Azusa Ito, Masayuki Yasuda, Shojiro Sawada, Keiichi Kondo, Chihiro Satake, Hideki Katagiri, Toru Nakazawa

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Relationship between nailfold capillaroscopy parameters and the severity of diabetic retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  5. Article
  6. Diabetes and carotid artery disease: a narrative review.Annals of translational medicine · 2020
    Review
  7. Observational
  8. Article
  9. Lateral Strain Patterns at the Sphenobasilar Synchondrosis.The Journal of the American Osteopathic Association · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kohei IchinohasamaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hiroshi KunikataDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.ORCID 0000-0003-0642-793X
Azusa ItoDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Masayuki YasudaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Shojiro SawadaDepartment of Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai, Japan.
Keiichi KondoDepartment of Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai, Japan.
Chihiro SatakeDepartment of Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hideki KatagiriDepartment of Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai, Japan.
Toru NakazawaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare clinical findings, including ocular blood flow and intima-media thickness (IMT) of the carotid artery, in mild nonproliferative diabetic retinopathy (NPDR) and no diabetic retinopathy (NDR) patients, and to determine risk factors contributing to mild NPDR.

methodsIn 129 subjects (129 eyes) with type-2 diabetes patients and mild NPDR or NDR, standard statistical techniques were used to determine associations between clinical findings, including diabetes duration, blood levels of creatinine and hemoglobin A1c (HbA1c), central macular thickness (CMT; measured with optical coherence tomography), mean blur rate (MBR; measured with laser speckle flowgraphy), and ultrasound-measured carotid IMT.

resultsDiabetes duration, IMT, and CMT were significantly higher in the mild NPDR patients than the NDR patients (

conclusionsIncreased IMT showed a close association with ocular ischemia in patients with type-2 diabetes and contributed to the presence of mild NPDR. These findings suggest that IMT may be an early biomarker of mild NPDR.

Identifiers

PMID30915237
PMCPMC6402216
OpenAlexW2915508448

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.