Evidence map›Paper›PMID 30915143›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2019

A New Perspective of Acupuncture: The Interaction among Three Networks Leads to Neutralization.

Ning-Cen Li, Ming-Yue Li, Bo Chen, Yi Guo

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Adenosine triphosphate mediates the pain tolerance effect of manual acupuncture at Zusanli (ST36) in mice.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024
    Article
  7. Acupuncture improves the live birth of patients with repeated implantation failure: a retrospective cohort study.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Anatomical features of the GV20 acupoint.Integrative medicine research · 2023
    Article
  12. Identifying Key Node with Motif-Based PageRank on Acupoint-Disease Network.Evidence-based complementary and alternative medicine : eCAM · 2023
    Article
  13. Article
  14. Review
  15. The Efficacy of Acupuncture on Patients with Erectile Dysfunction: A Review.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ning-Cen LiAcupuncture and Moxibustion College of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Ming-Yue LiAcupuncture and Moxibustion College of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Bo ChenAcupuncture and Moxibustion College of Tianjin University of Traditional Chinese Medicine, Tianjin, China.ORCID 0000-0003-2420-4764
Yi GuoAcupuncture Research Center of Tianjin University of Traditional Chinese Medicine, Tianjin, China.ORCID 0000-0002-4961-3073
Tianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acupuncture has been used to treat multiple medical conditions, but whether the diverse effects of acupuncture are intrinsically linked and how they might be connected have yet to be determined. More and more researches have shown that acupuncture is a kind of nociceptive stimulus, which can cause inflammatory reaction in the sites of acupuncture and then further activate the nerve-endocrine-immune systems to cause the cascade amplification of the acupuncture effect. This review seeks to provide a comprehensive summary of the existing literature concerning the role of "acupoint-meridian-disease network" in various effects of acupuncture and suggest a novel notion that acupuncture may restore homeostasis under different pathological conditions by regulating this network, resulting in the activation of different reaction cascades in response to pathological injury. We think that acupuncture acts on acupoints, first activating the small network of acupoints (Acupoint Network). The information of acupuncture is amplified by cascade, and the nerve endocrine immune system (NEI) is activated through the large network of meridians (Meridian Network) of the body itself. The nerve-endocrine-immune system (NEI) further outputs the effect information to the target organ through multilevel and multisystems and finally acts on the disease network (Disease Network) to produce acupuncture effect.

Identifiers

PMID30915143
PMCPMC6409053
OpenAlexW2915930122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.