Evidence map›Paper›PMID 30915081›Full record

ReviewFrontiers in immunology2019

Mutating for Good: DNA Damage Responses During Somatic Hypermutation.

Bas Pilzecker, Heinz Jacobs

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Separating selection from mutation in antibody language models.bioRxiv : the preprint server for biology · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Prime Editing in Dividing and Quiescent Cells.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Lipid metabolism in B cell biology.Molecular oncology · 2024
    Review
  19. Review
  20. Analysis of Mutational Status ofInternational journal of molecular sciences · 2024
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bas PilzeckerDivision of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, Netherlands.
Heinz JacobsDivision of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, Netherlands.
Oncode Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Somatic hypermutation (SHM) of immunoglobulin (

Indexed as

AICDA (Activation-Induced Cytidine Deaminase)B-LymphocytesCytidine DeaminaseDeaminationDNADNA DamageDNA RepairHumansSomatic Hypermutation, ImmunoglobulinVDJ ExonsAICDA (Activation-Induced Cytidine Deaminase)Cytidine DeaminaseDNAabasic sitebase excision repaircytosine deaminationDNA damage tolerance (DDT)non-canonical mismatch repair (ncMMR)translesion synthesis (TLS)

Identifiers

PMID30915081
PMCPMC6423074
OpenAlexW2920915242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.