Evidence map›Paper›PMID 30915072›Full record

ReviewFrontiers in immunology2019

Physiological Regulation of Innate Lymphoid Cells.

Nicolas Jacquelot, Kylie Luong, Cyril Seillet

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Androgens Modulate the Immune Profile in a Mouse Model of Polycystic Ovary Syndrome.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  7. Review
  8. Review
  9. The Influence of Sex Hormones and X Chromosome in Immune Responses.Current topics in microbiology and immunology · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Intestinal Infection ofFrontiers in microbiology · 2021
    Review
  16. Review
  17. Animal Models ofFrontiers in immunology · 2020
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicolas JacquelotMolecular Immunology Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Kylie LuongMolecular Immunology Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Cyril SeilletMolecular Immunology Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Walter and Eliza Hall Institute of Medical Research · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discovery of innate lymphoid cells (ILCs) have provoked a paradigm shift in our understanding of the immune protection. Their constitutive presence and activity at the body's barrier surfaces ensure the maintenance of the tissue homeostasis and immune protection. This complex family has distinct and non-redundant functions that can have both beneficial and detrimental effects on disease outcome. The capacity of ILCs to perform their function effectively relies on their ability to sense and integrate intrinsic and extrinsic signals. Recent studies have shown that ILCs are not only sensitive to pathogen-derived stimuli but are also very well equipped to sense host-derived signals such as neuropeptides, hormones, and metabolites. The integration of these signals represents a complex and constant cross-talk between the immune system and the physiological systems of the body, including the nervous, endocrine, digestive, and reproductive systems. The physiological regulation of ILCs constitutes an important step in our understanding of the events leading to the protective and pathological properties of these cells. This review summarizes the recent advances in the understanding of the regulation of ILCs by physiological signals and their consequences on the maintenance of tissue homeostasis.

Indexed as

Immunity, InnateAnimalsEicosanoidsHomeostasisHormonesHumansLymphocytesMiceNeuropeptidesNeurosecretory SystemsSignal TransductionEicosanoidsHormonesNeuropeptideshomeostasishormonesimmunityinnate lymphoid cellsmetabolitesneuroendocrine regulationneuropeptides

Identifiers

PMID30915072
PMCPMC6422966
OpenAlexW2921634897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.