Evidence map›Paper›PMID 30915071›Full record

ArticleFrontiers in immunology2019

Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway.

Faruk Ramadani, Holly Bowen, Hannah J Gould, David J Fear

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Whence and wherefore IgE?Immunological reviews · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. B cell receptor ligation induces IgE plasma cell elimination.The Journal of experimental medicine · 2023
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Faruk RamadaniRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London, United Kingdom.
Holly BowenRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London, United Kingdom.
Hannah J GouldRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London, United Kingdom.
David J FearAsthma UK Centre, Allergic Mechanisms in Asthma, King's College London, London, United Kingdom.
Asthma UK · GBKing's College London · GB

Funding

Medical Research Council G0200486Medical Research Council G0501494Medical Research Council G1000758Medical Research Council G1100090Medical Research Council MC_PC_16048Medical Research Council MR/M022943/1
6 · The paper itself

Abstract

IgE is secreted by plasma cells (PCs) and is central to allergic disease. Using an

Indexed as

ApoptosisCell DifferentiationCells, CulturedEarly Growth Response Protein 1Gene Expression RegulationGene Regulatory NetworksGerminal CenterHumansHypersensitivityImmunoglobulin EImmunoglobulin GInterferon Regulatory Factor-4Interferon Regulatory FactorsPalatine TonsilPhenotypePlasma CellsEarly Growth Response Protein 1EGR1 protein, humanImmunoglobulin EImmunoglobulin GInterferon Regulatory Factor-4Interferon Regulatory Factorsallergic diseaseapoptosiscell cyclinggene expressionhuman IgE+ B cellsIgE+ plasma cell differentiationtranscriptomics

Identifiers

PMID30915071
PMCPMC6421273
OpenAlexW2921119941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.