ArticleFrontiers in neuroscience2019
Somatosensory Stimulation With XNKQ Acupuncture Modulates Functional Connectivity of Motor Areas.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An overview of the evidence to guide decision-making in acupuncture therapies for early recovery after acute ischemic stroke.Frontiers in neurology · 2022Pooled it
- Acute prefrontal hemodynamic responses to Xingnao Kaiqiao acupuncture in healthy participants and patients with prolonged disorders of consciousness.Frontiers in neurology · 2026Article
- The Effect of Integrative Treatment on Improving Functional Level in Stroke Patients: A Retrospective Chart Review.Healthcare (Basel, Switzerland) · 2025Article
- Electroacupuncture Inhibits Ferroptosis by Modulating Iron Metabolism and Oxidative Stress to Alleviate Cerebral Ischemia-Reperfusion Injury.Journal of molecular neuroscience : MN · 2025Article
- Evaluating post-thrombectomy effective connectivity changes in anterior circulation stroke.Annals of clinical and translational neurology · 2024Article
- Effects of anterior sciatic nerve acupuncture on lower limb paralysis after cerebral infarction: study protocol for a randomized controlled trial.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Article
- A multimodal MRI study of XNKQ acupuncture for limb dysfunction after ischemic stroke: a randomized controlled study protocol.Frontiers in neurology · 2024Article
- New insights into acupuncture techniques for poststroke spasticity.Frontiers in public health · 2023Review
- Acupuncture mechanism studies employing task-based fMRI: a scoping review protocol.Systematic reviews · 2022Article
- Mechanism of Electroacupuncture Against Cerebral Ischemia-Reperfusion Injury: Reducing Inflammatory Response and Cell Pyroptosis by Inhibiting NLRP3 and Caspase-1.Frontiers in molecular neuroscience · 2022Article
- Frequency-Specific Changes of Amplitude of Low-Frequency Fluctuations in Patients with Acute Basal Ganglia Ischemic Stroke.Neural plasticity · 2022Article
- Resting-State fMRI in Studies of Acupuncture.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Article
- Scalp Acupuncture Enhances the Functional Connectivity of Visual and Cognitive-Motor Function Network of Patients with Acute Ischemic Stroke.Evidence-based complementary and alternative medicine : eCAM · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Xingnao Kaiqiao (XNKQ) acupuncture is an acupuncture technique used for stroke patients. In 24 healthy volunteers, we applied this complex acupuncture intervention, which consists of a manual needle-stimulation on five acupuncture points (DU26 unilaterally, PC6, and SP6 bilaterally). XNKQ was compared to three control conditions: (1) insertion of needles on the XNKQ acupuncture points without stimulation, (2) manual needle-stimulation on five nearby non-acupuncture points, and (3) insertion of needles on the non-acupuncture points without stimulation. In a within-subject design, we investigated functional connectivity changes in resting-state functional magnetic resonance imaging (fMRI) by means of the data-driven eigenvector centrality (EC) approach. With a 2 × 2 factorial within-subjects design with two-factor stimulation (stimulation vs. non-stimulation) and location (acupuncture points vs. non-acupuncture points), we found decreased EC in the precuneus after needle-stimulation (stimulation<non-stimulation), whereas the factor location showed no statistically significant EC differences. XNKQ acupuncture compared with needle-stimulation on non-acupuncture points showed decreased EC primarily in subcortical structures such as the caudate nucleus, subthalamic nucleus, and red nucleus.
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