Evidence map›Paper›PMID 30914775›Full record

ArticleScientific reports2019

Keggin-type polyoxotungstates as mushroom tyrosinase inhibitors - A speciation study.

Joscha Breibeck, Nadiia I Gumerova, Benedikt B Boesen, Mathea Sophia Galanski, Annette Rompel

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Promising application of polyoxometalates in the treatment of cancer, infectious diseases and Alzheimer's disease.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joscha BreibeckUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Althanstraße 14, 1090, Wien, Austria.ORCID http://orcid.org/0000-0002-7210-5261
Nadiia I GumerovaUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Althanstraße 14, 1090, Wien, Austria.ORCID http://orcid.org/0000-0003-4375-0103
Benedikt B BoesenUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Althanstraße 14, 1090, Wien, Austria.ORCID http://orcid.org/0000-0003-1010-3671
Mathea Sophia GalanskiUniversität Wien, Fakultät für Chemie, Institut für Anorganische Chemie, Währinger Str. 42, 1090, Wien, Austria.ORCID http://orcid.org/0000-0001-7965-7379
Annette RompelUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Althanstraße 14, 1090, Wien, Austria. annette.rompel@univie.ac.at.ORCID http://orcid.org/0000-0002-5919-0553

Funding

Austrian Science Fund FWF M 2203Austrian Science Fund FWF P 25217Austrian Science Fund FWF P 27534
6 · The paper itself

Abstract

Mushroom tyrosinase abPPO4 is a commercially relevant polyphenol oxidase and has been being targeted for numerous inhibition studies including polyoxometalates (POMs). In the present work, its diphenolase activity was inhibited at pH 6.8 by a series of structurally related polyoxotungstates (POTs) of the α-Keggin archetype, exhibiting the general formula [X

Indexed as

AgaricalesAnionsEnzyme InhibitorsHydrogen-Ion ConcentrationHydrolysisKineticsMagnetic Resonance SpectroscopyMonophenol MonooxygenaseReproducibility of ResultsTungsten CompoundsAnionsEnzyme InhibitorsMonophenol MonooxygenaseTungsten Compounds

Identifiers

PMID30914775
PMCPMC6435698

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.