Evidence map›Paper›PMID 30914754›Full record

ArticleScientific reports2019

PMCA-replicated PrP

Ignazio Cali, Jody Lavrich, Fabio Moda, Diane Kofskey, Satish Kumar Nemani, Brian Appleby, Fabrizio Tagliavini, Claudio Soto, Pierluigi Gambetti, Silvio Notari

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 49 citations in OpenAlex.

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  11. Two distinct conformers of PrPActa neuropathologica communications · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ignazio CaliCase Western Reserve University, Department of Pathology, Cleveland, Ohio, USA.
Jody LavrichCase Western Reserve University, Department of Pathology, Cleveland, Ohio, USA.
Fabio ModaFondazione IRCCS Istituto Neurologico Carlo Besta, Neurology 5 and Neuropathology Unit, Milano, Italy.
Diane KofskeyCase Western Reserve University, Department of Pathology, Cleveland, Ohio, USA.
Satish Kumar NemaniCase Western Reserve University, Department of Pathology, Cleveland, Ohio, USA.
Brian ApplebyCase Western Reserve University, National Prion Disease Pathology Surveillance Center and Departments of Neurology and Psychiatry, Cleveland, Ohio, USA.
Fabrizio TagliaviniFondazione IRCCS Istituto Neurologico Carlo Besta, Neurology 5 and Neuropathology Unit, Milano, Italy.
Claudio SotoUniversity of Texas Health Science Center, Department of Neurology, Houston, Texas, USA.
Pierluigi GambettiCase Western Reserve University, Department of Pathology, Cleveland, Ohio, USA. pxg13@case.edu.
Silvio NotariCase Western Reserve University, Department of Pathology, Cleveland, Ohio, USA. sxn194@case.edu.
Case Western Reserve University · USFondazione IRCCS Istituto Neurologico Carlo Besta · ITThe University of Texas Health Science Center at Houston · US

Funding

Neuropathology Core - P GambettiP01AI106705 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI GAMBETTI, PIERLUIGI · 2014 to 2018
$7.7M
Structural correlates of prion strain, phenotype and infectivity in human prion dR01NS083687 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI GAMBETTI, PIERLUIGI, SUREWICZ, WITOLD K · 2014 to 2018
$2.9M
NIAID NIH HHS P01 AI106705NINDS NIH HHS R01 NS083687
6 · The paper itself

Abstract

The presence of abnormal, disease-related prion protein (PrP

Indexed as

Protein FoldingAnimalsBrainCreutzfeldt-Jakob SyndromeHumansMice, TransgenicPrion ProteinsPrionsProtein StabilityPrion ProteinsPrions

Identifiers

PMID30914754
PMCPMC6435672
OpenAlexW2924252871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.