ArticleScientific reports2019
Analysis of fluoroquinolones in dusts from intensive livestock farming and the co-occurrence of fluoroquinolone-resistant Escherichia coli.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 60 citations in OpenAlex.
- Antimicrobial Activity of Metal-Based Danofloxacin Complexes Against Pathogenic Microorganisms.Molecules (Basel, Switzerland) · 2026Article
- Characteristics of quinolone resistance in Escherichia coli isolated from wildlife in Poland.Scientific reports · 2025Article
- Article
- Mapping the spread of fluoroquinolone resistance: continued presence of non-susceptibleFrontiers in veterinary science · 2025Article
- Veterinary Drug Residues in the Food Chain as an Emerging Public Health Threat: Sources, Analytical Methods, Health Impacts, and Preventive Measures.Foods (Basel, Switzerland) · 2024Review
- Geographical distribution of mobile genetic elements in microbial communities along the Yucatan coast.PloS one · 2024Article
- Distribution of Fluoroquinolone-ResistantThe journal of poultry science · 2024Article
- Molecularly Imprinted Magnetic Nanocomposite Based on Carboxymethyl Dextrin for Removal of Ciprofloxacin Antibiotic from Contaminated Water.Nanomaterials (Basel, Switzerland) · 2023Article
- Occurrence and Biological Cost ofAntibiotics (Basel, Switzerland) · 2022Article
- Treatment of pigs with enrofloxacin via different oral dosage forms - environmental contaminations and resistance development ofJournal of veterinary science · 2022Article
- Comparison of approaches for source attribution of ESBL-producing Escherichia coli in Germany.PloS one · 2022Article
- Identification and Characterization of HD1, a Novel Ofloxacin-DegradingFrontiers in microbiology · 2022Article
- Animal source food eating habits of outpatients with antimicrobial resistance in Bukavu, D.R. Congo.Antimicrobial resistance and infection control · 2021Article
- Prevalence of IncFIB Plasmids Found amongPathogens (Basel, Switzerland) · 2021Article
- Role played by the environment in the emergence and spread of antimicrobial resistance (AMR) through the food chain.EFSA journal. European Food Safety Authority · 2021Article
- Distribution of Flumequine in Intestinal Contents and Colon Tissue in Pigs after Its Therapeutic Use in the Drinking Water.Animals : an open access journal from MDPI · 2021Article
- Antimicrobial resistance at the human-animal interface in the Pastoralist Communities of Kasese District, South Western Uganda.Scientific reports · 2020Article
- Occurrence of extended-spectrum beta-lactamase-producing Enterobacteriaceae, microbial loads, and endotoxin levels in dust from laying hen houses in Egypt.BMC veterinary research · 2020Article
- Enhanced reductive removal of ciprofloxacin in pharmaceutical wastewater using biogenic palladium nanoparticles by bubbling HRSC advances · 2020Article
- Effects of enrofloxacin treatment on the bacterial microbiota of milk from goats with persistent mastitis.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluoroquinolones are important therapeutics in human and veterinary medicine. This study aimed to retrospectively analyse sedimentation dusts from intensive-livestock-farming barns for fluoroquinolones and investigate the association between resistant Escherichia coli and the detected drugs. Sedimentation-dust samples (n = 125) collected (1980-2009) at 14 barns of unknown-treatment status were analysed by HPLC and tandem-mass spectroscopy to detect enrofloxacin, ciprofloxacin, marbofloxacin, and difloxacin. Recent microbiological data were included to investigate the relationship between fluoroquinolone presence and fluoroquinolone-resistant E. coli. Fifty-nine dust samples (47%) from seven barns contained fluoroquinolone residues. Up to three different fluoroquinolones were detected in pig and broiler barns. Fluoroquinolone concentrations ranged from 10-pg/mg to 46-ng/mg dust. Fluoroquinolone-resistant E. coli were isolated from four barns. Of all the dust samples, 22% contained non-susceptible isolates. Non-susceptible isolate presence in the dust was significantly associated (p = 0.0283) with detecting the drugs, while drug detection increased the odds (4-fold) of finding non-susceptible E. coli (odds ratio = 3.9877, 95% CI: 1.2854-12.3712). This retrospective study shows that fluoroquinolone usage leads to dust contamination. We conclude that farmers and animals inhale/swallow fluoroquinolones and fluoroquinolone-resistant bacteria due to drug application. Furthermore, uncontrolled drug emissions via air exhausted from the barns can be assumed.
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