Evidence map›Paper›PMID 30914669›Full record

ArticleScientific reports2019

Utilizing general human movement models to predict the spread of emerging infectious diseases in resource poor settings.

M U G Kraemer, N Golding, D Bisanzio, S Bhatt, D M Pigott, S E Ray, O J Brady, J S Brownstein, N R Faria, D A T Cummings and 5 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Trial
  2. Characterizing the impact of incorporating spatially aggregated human mobility data into infectious disease models.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. [Environmental medicine and AI, migration, and emerging and reemerging diseases in Mexico].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Toward optimal disease surveillance with graph-based active learning.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Spatial Interaction Analysis of Infectious Disease Import and Export between Regions.International journal of environmental research and public health · 2024
    Article
  14. Infectious Disease Modelling · 2024
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

M U G KraemerDepartment of Zoology, University of Oxford, Oxford, UK. moritz.kraemer@zoo.ox.ac.uk.
N GoldingDepartment of BioSciences, University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0001-8916-5570
D BisanzioRTI International, Washington, D.C., USA.
S BhattImperial College London, London, United Kingdom.ORCID 0000-0002-0891-4611
D M PigottInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
S E RayInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.ORCID 0000-0002-5775-8344
O J BradyCentre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
J S BrownsteinHarvard Medical School, Boston, MA, USA.
N R FariaDepartment of Zoology, University of Oxford, Oxford, UK.ORCID 0000-0002-9747-8822
D A T CummingsDepartment of Biology, University of Florida, Gainesville, FL, USA.
O G PybusDepartment of Zoology, University of Oxford, Oxford, UK.
D L SmithInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.ORCID 0000-0003-4367-3849
A J TatemWorldPop, Department of Geography and Environmental Sciences, University of Southampton, Southampton, UK.
S I HayInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA. sihay@uw.edu.ORCID 0000-0002-0611-7272
R C ReinerInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA. bcreiner@uw.edu.

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY · 2010 to 2026
$29.3M
Training, Outreach & Diversity ComponentU54GM088491 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAKOSKI, JOAN M · 2009 to 2018
$16.7M
RESEARCH TRAINING IN PEDIATRIC EMERGENCY MEDICINET32HD040128 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI Kenneth D. Mandl · 2001 to 2026
$5.0M
A Platform for Modeling the Global Impact of Climate Change on Infectious DiseaseR01LM010812 · NLM · BOSTON CHILDREN'S HOSPITAL · PI BROWNSTEIN, JOHN S. · 2010 to 2015
$2.5M
An Approach for Estimating Foodborne Illnesses and Assessing Risk FactorsR01LM011965 · NLM · BOSTON CHILDREN'S HOSPITAL · PI BROWNSTEIN, JOHN S., NSOESIE, ELAINE O. · 2015 to 2018
$1.4M
Medical Research Council MR/R015600/1NIAID NIH HHS U19 AI089674NICHD NIH HHS T32 HD040128NIGMS NIH HHS U54 GM088491NLM NIH HHS R01 LM010812NLM NIH HHS R01 LM011965Wellcome TrustWellcome Trust 095066Wellcome Trust 10688/Z/15/ZWellcome Trust 206471/Z/17/Z
6 · The paper itself

Abstract

Human mobility is an important driver of geographic spread of infectious pathogens. Detailed information about human movements during outbreaks are, however, difficult to obtain and may not be available during future epidemics. The Ebola virus disease (EVD) outbreak in West Africa between 2014-16 demonstrated how quickly pathogens can spread to large urban centers following one cross-species transmission event. Here we describe a flexible transmission model to test the utility of generalised human movement models in estimating EVD cases and spatial spread over the course of the outbreak. A transmission model that includes a general model of human mobility significantly improves prediction of EVD's incidence compared to models without this component. Human movement plays an important role not only to ignite the epidemic in locations previously disease free, but over the course of the entire epidemic. We also demonstrate important differences between countries in population mixing and the improved prediction attributable to movement metrics. Given their relative rareness, locally derived mobility data are unlikely to exist in advance of future epidemics or pandemics. Our findings show that transmission patterns derived from general human movement models can improve forecasts of spatio-temporal transmission patterns in places where local mobility data is unavailable.

Indexed as

EbolavirusHuman MigrationModels, BiologicalAfrica, WesternHemorrhagic Fever, EbolaHumans

Identifiers

PMID30914669
PMCPMC6435716

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.