Evidence map›Paper›PMID 30914511›Full record

ArticlemBio2019

Rapid Replacement of Acinetobacter baumannii Strains Accompanied by Changes in Lipooligosaccharide Loci and Resistance Gene Repertoire.

Mark D Adams, Meredith S Wright, James K Karichu, Pratap Venepally, Derrick E Fouts, Agnes P Chan, Sandra S Richter, Michael R Jacobs, Robert A Bonomo

Abstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. In Silico Identification and Molecular Characterization ofAntibiotics (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Antimicrobial agents and chemotherapy · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. An Outbreak ofAntibiotics (Basel, Switzerland) · 2021
    Article
  19. Article
  20. Interaction ofAntibiotics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mark D AdamsThe J. Craig Venter Institute, La Jolla, California, USA mark.adams@jax.org.ORCID 0000-0003-3161-7460
Meredith S WrightThe J. Craig Venter Institute, La Jolla, California, USA.
James K KarichuDepartment of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Pratap VenepallyThe J. Craig Venter Institute, Rockville, Maryland, USA.
Derrick E FoutsThe J. Craig Venter Institute, Rockville, Maryland, USA.ORCID 0000-0003-4323-7668
Agnes P ChanThe J. Craig Venter Institute, Rockville, Maryland, USA.
Sandra S RichterDepartment of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Michael R JacobsDepartment of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Robert A BonomoDepartment of Medicine, Case Western Reserve University and CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology, Cleveland, Ohio, USA.

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
The J. Craig Venter Institute Genome Center for Infectious DiseasesU19AI110819 · NIAID · J. CRAIG VENTER INSTITUTE, INC. · PI TAN, GENE · 2014 to 2018
$29.7M
Understanding B-Lactam Resistance in Acinetobacter baumanniiR01AI072219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ROBERT A. BONOMO, Philip N. Rather · 2007 to 2026
$6.6M
Understanding ceftazidime resistance in SHV B-LactamasesR01AI063517 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A. · 2005 to 2023
$4.9M
A Mechanism-Based Approach to Metallo-beta-Lactamase InhibitionR01AI100560 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., SPENCER, JAMES · 2012 to 2022
$4.4M
The Continuing Challenge of Carbapenemases in K. pneumoniae: KPC-2 & NDM-1I01BX001974 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI BONOMO, ROBERT A. · 2013 to 2024
–
BLRD VA I01 BX001974NIAID NIH HHS R01 AI063517NIAID NIH HHS R01 AI072219NIAID NIH HHS R01 AI100560NIAID NIH HHS U19 AI110819NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

The population structure of health care-associated pathogens reflects patterns of diversification, selection, and dispersal over time. Empirical data detailing the long-term population dynamics of nosocomial pathogens provide information about how pathogens adapt in the face of exposure to diverse antimicrobial agents and other host and environmental pressures and can inform infection control priorities. Extensive sequencing of clinical isolates from one hospital spanning a decade and a second hospital in the Cleveland, OH, metropolitan area over a 3-year time period provided high-resolution genomic analysis of the

Indexed as

Drug Resistance, BacterialMicrobiotaAcinetobacter baumanniiAcinetobacter InfectionsCross InfectionDisease Transmission, InfectiousGenetic VariationGenotypeHospitalsLipopolysaccharidesMolecular EpidemiologyOhioPhylogenyVirulence Factorslipid-linked oligosaccharidesLipopolysaccharidesVirulence FactorsAcinetobacterantibiotic resistancegenome analysis

Identifiers

PMID30914511
PMCPMC6437055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.