Evidence map›Paper›PMID 30914434›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2019

Interactions of

Hui-Yi Lin, Catherine Y Callan, Zhide Fang, Heng-Yuan Tung, Jong Y Park

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  5. NInternational journal of oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hui-Yi LinBiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, Louisiana. hlin1@lsuhsc.edu.ORCID 0000-0002-3307-5549
Catherine Y CallanBiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Zhide FangBiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Heng-Yuan TungBiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Jong Y ParkDepartment of Cancer Epidemiology, Moffitt Cancer Center and Research Institute, Tampa, Florida.ORCID 0000-0002-6384-6447
Louisiana State University Health Sciences Center New Orleans · USMoffitt Cancer Center · US

Funding

Gene-Gene Interactions and Their Functional Roles in Prostate Cancer AggressivenessR21CA202417 · NCI · LSU HEALTH SCIENCES CENTER · PI LIN, HUI-YI · 2016 to 2017
$284k
NCI NIH HHS R21 CA202417
6 · The paper itself

Abstract

backgroundAfrican American (AA) men have a higher risk of developing prostate cancer than white men. SNPs are known to play an important role in developing prostate cancer. The impact of

methodsWe evaluated 205 SNPs using the 2,253 prostate cancer patients and 2,423 controls and applied multiphase (discovery-validation) design. In addition to SNP individual effects, SNP-SNP interactions were evaluated using the SNP Interaction Pattern Identifier, which assesses 45 patterns.

resultsThree SNPs (rs9642880, rs16902359, and rs12680047) and 79 SNP-SNP pairs were significantly associated with prostate cancer risk. These two SNPs (rs16902359 and rs9642880) in

conclusionsNovel SNP-SNP interactions in the IMPACT: This gene-gene interaction between

Indexed as

Biomarkers, TumorBlack or African AmericanCase-Control StudiesEpistasis, GeneticFollow-Up StudiesGenes, mycGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMalePolymorphism, Single NucleotidePrognosisProspective StudiesProstatic NeoplasmsProto-Oncogene Proteins c-mycRisk FactorsBiomarkers, Tumorlong noncoding RNA CASC11, humanMYC protein, humanProto-Oncogene Proteins c-mycPVT1 long-non-coding RNA, humanRNA, Long Noncoding

Identifiers

PMID30914434
PMCPMC6548667
OpenAlexW2924842355

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.