ArticleClinical cancer research : an official journal of the American Association for Cancer Research2019
Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast Cancer.
Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
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The trial behind it
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Who cites it
66 citing papers in PubMed, 101 citations in OpenAlex.
- The immunology of human breast cancer.Nature reviews. Immunology · 2026Review
- The dual immune landscape of homologous recombination-deficient tumors: mechanisms and therapeutic implications.Cancer metastasis reviews · 2026Review
- Reclassification ofCurrent oncology (Toronto, Ont.) · 2026Article
- Current evidence and emerging approaches in immunotherapy for gynecological cancers.Discover oncology · 2026Review
- Quantifying rate-limiting genetic variation in breast and ovarian tumourigenesis.EBioMedicine · 2026Article
- The cGAS-STING pathway in ovarian cancer: from genomic instability to immunotherapeutic vulnerability.Frontiers in immunology · 2026Review
- Comparative Genomic and Microenvironmental Profiles of Hereditary and Sporadic TNBC in Colombian Women.Biology · 2025Article
- Comprehensive genomic profiling of breast cancer reveals mutational landscape and the PEEKABOO model: a population-specific assessment tool for predicting germline mutations.Journal of translational medicine · 2025Article
- Case Report: Atypical Nodular Dermatofibrosis and Renal Cysts in a Bichon Frise with a BRCA2 Mutation and No FLCN Mutation.Animals : an open access journal from MDPI · 2025Article
- Tumor mutational burden status and clinical characteristics of invasive lobular carcinoma of the breast.Breast cancer (Tokyo, Japan) · 2025Article
- Thirty Years of BRCA1: Mechanistic Insights and Their Impact on Mutation Carriers.Cancer discovery · 2025Review
- Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma.Nature communications · 2025Article
- The evolving landscape of genetic biomarkers for immunotherapy in primary and metastatic breast cancer.Frontiers in oncology · 2025Article
- Resolving tumor microenvironment heterogeneity to forecast immunotherapy response in triple-negative breast cancer through multi-scale analysis.Frontiers in oncology · 2025Article
- Prominent protumoral cellular compartments of the tumor microenvironment in triple-negative breast cancer.Frontiers in cell and developmental biology · 2025Review
- Tumor analysis of BRCA carriers reveals genomic similarities although separated by time.Discover oncology · 2024Article
- The Tumour Microenvironment and Epigenetic Regulation inCancers · 2024Review
- Landscape of homologous recombination deficiency in gastric cancer and clinical implications for first-line chemotherapy.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024Article
- Deletions Rate-Limit Breast and Ovarian Cancer Initiation.bioRxiv : the preprint server for biology · 2024Article
- Development of 42 marker panel for in-depth study of cancer associated fibroblast niches in breast cancer using imaging mass cytometry.Frontiers in immunology · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
Abstract
purposeBreast cancers with EXPERIMENTAL
designWe hypothesized that genomic signatures might predict immunogenicity in
resultsWe found that homologous recombination deficiency (HRD) scores were negatively associated with expression-based immune indices [cytolytic index (
conclusionsHRD scores and hormone receptor subtype are predictive of immunogenicity in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.