Evidence map›Paper›PMID 30914253›Full record

ArticleArchives of biochemistry and biophysics2019

Alterations of elastin in female reproductive tissues arising from advancing parity.

Basant Dhital, Keith T Downing, Farhana Gul-E-Noor, Yakov Landau, Pratikkumar Rathod, Shari Hirsch, Emmanuel J Chang, Gregory S Boutis

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of biochemistry and biophysics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Basant DhitalDepartment of Physics, The Graduate Center of the City University of New York, NY, United States.
Keith T DowningMontefiore Medical Center-Albert Einstein College of Medicine, Department of Obstetrics and Gynecology and Women's Health, Division of Female Pelvic Medicine and Reconstructive Surgery, Bronx, NY, United States.
Farhana Gul-E-NoorDepartment of Physics, Brooklyn College of the City University of New York, Brooklyn, NY, United States.
Yakov LandauDepartment of Physics, Brooklyn College of the City University of New York, Brooklyn, NY, United States.
Pratikkumar RathodDepartment of Natural Sciences, LaGuardia Community College, the City University of New York, NY, United States.
Shari HirschDepartment of Physics, Brooklyn College of the City University of New York, Brooklyn, NY, United States.
Emmanuel J ChangDepartment of Chemistry, York College of the City University of New York, Jamaica, NY, United States; Department of Chemistry, The Graduate Center of the City University of New York, NY, United States; Department of Biochemistry, The Graduate Center of the City University of New York, NY, United States.
Gregory S BoutisDepartment of Physics, The Graduate Center of the City University of New York, NY, United States; Department of Physics, Brooklyn College of the City University of New York, Brooklyn, NY, United States; Department of Chemistry, The Graduate Center of the City University of New York, NY, United States; Department of Biochemistry, The Graduate Center of the City University of New York, NY, United States. Electronic address: gboutis@brooklyn.cuny.edu.
City University of New York · USBrooklyn College · USAlbert Einstein College of Medicine · USLaGuardia Community College · USThe Graduate Center, CUNY · US

Funding

Probing dynamics of water in elastin by q-space imaging and multiple quantum NMRSC1GM086268 · NIGMS · YORK COLLEGE · PI BOUTIS, GREGORY · 2009 to 2016
$2.2M
NIGMS NIH HHS SC1 GM086268
6 · The paper itself

Abstract

Female reproductive tissues undergo significant alterations during pregnancy, which may compromise the structural integrity of extracellular matrix proteins. Here, we report on modifications of elastic fibers, which are primarily composed of elastin and believed to provide a scaffold to the reproductive tissues, due to parity and parturition. Elastic fibers from the upper vaginal wall of virgin Sprague Dawley rats were investigated and compared to rats having undergone one, three, or more than five pregnancies. Optical microscopy was used to study fiber level changes. Mass spectrometry,

Indexed as

AnimalsDesmosineElastic TissueElastinFemaleMatrix Metalloproteinase 2Matrix Metalloproteinase 9Nuclear Magnetic Resonance, BiomolecularParityPeptide FragmentsPregnancyProtein Structure, SecondaryRatsRats, Sprague-DawleySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTissue Inhibitor of Metalloproteinase-1DesmosineElastinMatrix Metalloproteinase 2Matrix Metalloproteinase 9Mmp2 protein, ratMmp9 protein, ratPeptide FragmentsTIMP1 protein, ratTissue Inhibitor of Metalloproteinase-113C NMRDesmosineElastinELISAMALDI

Identifiers

PMID30914253
PMCPMC6529287
OpenAlexW2923174847

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.