Evidence map›Paper›PMID 30914224›Full record

ArticleVaccine2019

Vaccine-mediated protection of pigs against infection with pandemic H1N1 2009 swine influenza A virus requires a close antigenic match between the vaccine antigen and challenge virus.

Helen E Everett, Mario Aramouni, Vivien Coward, Andrew Ramsay, Michael Kelly, Sophie Morgan, Elma Tchilian, Laetitia Canini, Mark E J Woolhouse, Sarah Gilbert and 3 more

Abstract read
In one paragraph

Article in Vaccine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Helen E EverettVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone KT15 3NB, UK. Electronic address: helen.everett@apha.gsi.gov.uk.
Mario AramouniThe Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, UK.
Vivien CowardVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone KT15 3NB, UK.
Andrew RamsayVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone KT15 3NB, UK.
Michael KellyVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone KT15 3NB, UK.
Sophie MorganThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
Elma TchilianThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
Laetitia CaniniUniversity of Edinburgh, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
Mark E J WoolhouseUniversity of Edinburgh, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
Sarah GilbertThe Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, UK.
Bryan CharlestonThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
Ian H BrownVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone KT15 3NB, UK.
Sharon M BrookesVirology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone KT15 3NB, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/L001330/1Biotechnology and Biological Sciences Research Council BBS/E/I/00007031Biotechnology and Biological Sciences Research Council BBS/E/I/00007038
6 · The paper itself

Abstract

Swine influenza A virus (SwIV) infection has considerable economic and animal welfare consequences and, because of the zoonotic potential, can also have public health implications. The 2009 pandemic H1N1 'swine-origin' infection is now endemic in both pigs and humans. In Europe, avian-like H1

Indexed as

Immunogenicity, VaccineAnimalsAntigens, ViralCytokinesInfluenza A Virus, H1N1 SubtypeInfluenza VaccinesOrthomyxoviridae InfectionsSwineVaccines, InactivatedVirus SheddingAntigens, ViralCytokinesInfluenza VaccinesVaccines, InactivatedH1N1Immune responsePandemic 2009 influenza A virusSwine influenza A virusWhole inactivated virus vaccine

Identifiers

PMID30914224
PMCPMC6467548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.