Evidence map›Paper›PMID 30914045›Full record

ArticleBMC medicine2019

'Fit-for-purpose?' - challenges and opportunities for applications of blockchain technology in the future of healthcare.

Tim K Mackey, Tsung-Ting Kuo, Basker Gummadi, Kevin A Clauson, George Church, Dennis Grishin, Kamal Obbad, Robert Barkovich, Maria Palombini

Abstract read
In one paragraph

Article in BMC medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Biomedical blockchain with practical implementations and quantitative evaluations: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2024
    Pooled it
  3. Pooled it
  4. Applications of Blockchain in the Medical Field: Narrative Review.Journal of medical Internet research · 2021
    Pooled it
  5. Article
  6. Article
  7. Blockchain in Cancer Care: Toward Evidence-Based and Inclusive Practice.Asian Pacific journal of cancer prevention : APJCP · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Enhancing Cancer Care through Blockchain Technology.Asian Pacific journal of cancer prevention : APJCP · 2025
    Review
  12. Barriers to and Facilitators of Technology Adoption in Emergency Departments: A Comprehensive Review.International journal of environmental research and public health · 2025
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tim K MackeyDepartment of Anesthesiology and Division of Infectious Disease and Global Public Health, University of California, San Diego School of Medicine, San Diego, CA, USA. tmackey@ucsd.edu.ORCID 0000-0002-2191-7833
Tsung-Ting KuoUCSD Health Department of Biomedical Informatics, University of California San Diego, La Jolla, CA, USA.
Basker GummadiBayer Corporation, 100 Bayer Boulevard, Whippany, NJ, 07981, USA.
Kevin A ClausonDepartment of Pharmacy Practice, Lipscomb University College of Pharmacy & Health Sciences, Nashville, TN, USA.
George ChurchDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Dennis GrishinDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Kamal ObbadNebula Genomics, Inc., San Francisco, CA, USA.
Robert BarkovichProductive Consulting, Mountain View, CA, USA.
Maria PalombiniIEEE Standards Association, 445 Hoes Lane, Piscataway, NJ, 08854, USA.

Funding

BECKON - Block Estimate Chain: creating Knowledge ON demand & protecting privacyR00HG009680 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KUO, TSUNG-TING · 2019 to 2021
$849k
BECKON - Block Estimate Chain: creating Knowledge ON demand & protecting privacyK99HG009680 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KUO, TSUNG-TING · 2017 to 2018
$176k
NHGRI NIH HHS K99 HG009680NHGRI NIH HHS R00 HG009680
6 · The paper itself

Abstract

Blockchain is a shared distributed digital ledger technology that can better facilitate data management, provenance and security, and has the potential to transform healthcare. Importantly, blockchain represents a data architecture, whose application goes far beyond Bitcoin - the cryptocurrency that relies on blockchain and has popularized the technology. In the health sector, blockchain is being aggressively explored by various stakeholders to optimize business processes, lower costs, improve patient outcomes, enhance compliance, and enable better use of healthcare-related data. However, critical in assessing whether blockchain can fulfill the hype of a technology characterized as 'revolutionary' and 'disruptive', is the need to ensure that blockchain design elements consider actual healthcare needs from the diverse perspectives of consumers, patients, providers, and regulators. In addition, answering the real needs of healthcare stakeholders, blockchain approaches must also be responsive to the unique challenges faced in healthcare compared to other sectors of the economy. In this sense, ensuring that a health blockchain is 'fit-for-purpose' is pivotal. This concept forms the basis for this article, where we share views from a multidisciplinary group of practitioners at the forefront of blockchain conceptualization, development, and deployment.

Indexed as

Biomedical TechnologyComputer Communication NetworksManagement Information SystemsMedical InformaticsData WarehousingDelivery of Health CareElectronic Data ProcessingEquipment and Supplies UtilizationHigh-Throughput Screening AssaysHumansMedical RecordsBlockchainClinical trialsDistributed ledger technologyElectronic health recordsGenomicsHealthcare technologyHealth informaticsMedical licensureSupply chain

Identifiers

PMID30914045
PMCPMC6436239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.