ArticleProceedings. Biological sciences2019
Transmission ecology of canine parvovirus in a multi-host, multi-pathogen system.
Article in Proceedings. Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 48 citations in OpenAlex.
- Canine parvovirus in Africa: Explaining persistent disease despite vaccination.Veterinary and animal science · 2026Review
- Histopathological Myocardial Changes and CPV-2 DNA Detection in Young Dogs: A Retrospective Study.Veterinary sciences · 2026Article
- Development of canine parvovirus-2-based recombinant pseudoviruses expression system: a potential vaccine platform.Veterinary research · 2026Article
- Surveillance of Parvovirus in Free-Roaming Dogs in the Qinling Mountains and Assessment of the Risk of Cross-Species Transmission to Giant Pandas.Animals : an open access journal from MDPI · 2026Article
- Evaluating Protoparvovirus carnivoran1 Risk in Wild Carnivorans and Hunting Dogs in the Valencian Community, Eastern Spain.Transboundary and emerging diseases · 2026Article
- Association Study on Risk Factors for Major Infectious Diseases in Dogs and Cats in Shenzhen, China.Animals : an open access journal from MDPI · 2025Article
- Isolation and genetic characterization of parvovirus from Bengal tiger in China.Virology journal · 2025Article
- Red Foxes (Microorganisms · 2025Article
- High-throughput microfluidic real-time PCR as a promising tool in disease ecology.The Journal of animal ecology · 2025Article
- Overview of Recent Advances in Canine Parvovirus Research: Current Status and Future Perspectives.Microorganisms · 2024Review
- Feline Panleukopenia Virus in a Marsican Brown Bear and Crested Porcupine, Italy, 2022-2023.Emerging infectious diseases · 2024Article
- First identification of canine parvovirus -2a/2b variant in unvaccinated domestic dogs with gastrointestinal signs in Türkiye.Veterinary medicine and science · 2024Article
- Protoparvovirus carnivoran 1 infection of golden jackals Canis aureus in Serbia.Veterinary research communications · 2024Article
- Fatal canine parvovirus type 2a and 2c infections in wild Chinese pangolins (Manis pentadactyla) in southern China.Transboundary and emerging diseases · 2022Article
- The Importance of Accurate Host Species Identification in the Framework of Rabies Surveillance, Control and Elimination.Viruses · 2022Article
- A Three-Year Biocrime Sanitary Surveillance on Illegally Imported Companion Animals.Pathogens (Basel, Switzerland) · 2021Article
- Molecular Characteristics ofPathogens (Basel, Switzerland) · 2021Article
- Risk and Environmental Factors Associated with the Presence of Canine Parvovirus Type 2 in Diarrheic Dogs from Thessaly, Central Greece.Pathogens (Basel, Switzerland) · 2021Article
- First report of canine parvovirus molecular detection in Bangladesh.Veterinary world · 2021Article
- Domestic Dogs and Wild Foxes Interactions in a Wildlife-Domestic Interface of North-Central Chile: Implications for Multi-Host Pathogen Transmission.Frontiers in veterinary science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 8 institutions in 3 countries.
Funding
Abstract
Understanding multi-host pathogen maintenance and transmission dynamics is critical for disease control. However, transmission dynamics remain enigmatic largely because they are difficult to observe directly, particularly in wildlife. Here, we investigate the transmission dynamics of canine parvovirus (CPV) using state-space modelling of 20 years of CPV serology data from domestic dogs and African lions in the Serengeti ecosystem. We show that, although vaccination reduces the probability of infection in dogs, and despite indirect enhancement of population seropositivity as a result of vaccine shedding, the vaccination coverage achieved has been insufficient to prevent CPV from becoming widespread. CPV is maintained by the dog population and has become endemic with approximately 3.5-year cycles and prevalence reaching approximately 80%. While the estimated prevalence in lions is lower, peaks of infection consistently follow those in dogs. Dogs exposed to CPV are also more likely to become infected with a second multi-host pathogen, canine distemper virus. However, vaccination can weaken this coupling, raising questions about the value of monovalent versus polyvalent vaccines against these two pathogens. Our findings highlight the need to consider both pathogen- and host-level community interactions when seeking to understand the dynamics of multi-host pathogens and their implications for conservation, disease surveillance and control programmes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.