Evidence map›Paper›PMID 30913405›Full record

ArticleDevelopmental cell2019

Repurposing Kinetochore Microtubule Attachment Machinery in Neurodevelopment.

Rosalind Norkett, Wen Lu, Vladimir I Gelfand

Abstract readComment
In one paragraph

Article in Developmental cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Rosalind NorkettDepartment of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Wen LuDepartment of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Vladimir I GelfandDepartment of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: vgelfand@northwestern.edu.

Funding

REGULATION OF MYOSIN DRIVEN ORGANELLE TRANSPORTR01GM052111 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI GELFAND, VLADIMIR I · 1999 to 2018
$8.3M
Microtubule motors, cytoskeletal organization and cell polarityR35GM131752 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Vladimir I Gelfand · 2019 to 2026
$6.4M
NIGMS NIH HHS R01 GM052111NIGMS NIH HHS R35 GM131752
6 · The paper itself

Abstract

Kinetochore-microtubule attachments are essential to direct proper chromosome segregation during cell division. In this issue of Developmental Cell, Cheerambathur et al. (2019) and Zhao et al. (2019) uncover an unexpected role in neuronal development, unrelated to cell division, for components of the highly conserved kinetochore-microtubule attachment complex.

Indexed as

Chromosome SegregationKinetochoresMicrotubulesMorphogenesisNervous System

Identifiers

PMID30913405
PMCPMC7027935

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.