Evidence map›Paper›PMID 30913404›Full record

ArticleDevelopmental cell2019

Still Searching for Specialized Ribosomes.

Eric S Haag, Jonathan D Dinman

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Ribosomal protein paralogues in ribosome specialization.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  4. Impacts of ribosomal RNA sequence variation on gene expression and phenotype.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Eric S HaagDepartment of Biology, University of Maryland, College Park, MD 20742, USA. Electronic address: ehaag@umd.edu.
Jonathan D DinmanDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA. Electronic address: dinman@umd.edu.

Funding

X-linked Dyskeratosis Congenita and Ribosomal FrameshiftingR01HL119439 · NHLBI · UNIV OF MARYLAND, COLLEGE PARK · PI DINMAN, JONATHAN D, RUGGERO, DAVIDE · 2014 to 2017
$2.8M
NHLBI NIH HHS R01 HL119439
6 · The paper itself

Abstract

Reporting in Developmental Cell, Cenik et al. (2019) show that the maternal ribosome supply is sufficient for C. elegans embryonic development, arguing against tissue-specific specialized ribosomes in this context. Examination of ribosomal requirement with the genetic tool kit presented in Artiles et al. (2019) suggests a checkpoint that prevents uncoordinated growth.

Indexed as

Caenorhabditis elegansRibosomesAnimals

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.