Evidence map›Paper›PMID 30913289›Full record

ArticleGlycobiology2019

GRITS Toolbox-a freely available software for processing, annotating and archiving glycomics mass spectrometry data.

D Brent Weatherly, F Sena Arpinar, Melody Porterfield, Michael Tiemeyer, William S York, Rene Ranzinger

Abstract read
In one paragraph

Article in Glycobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Bioinformatics in Immunoglobulin Glycosylation Analysis.Experientia supplementum (2012) · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Software tools, databases and resources in metabolomics: updates from 2018 to 2019.Metabolomics : Official journal of the Metabolomic Society · 2020
    Review
  19. Tools for generating and analyzing glycan microarray data.Beilstein journal of organic chemistry · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

D Brent WeatherlyComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
F Sena ArpinarComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
Melody PorterfieldComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
Michael TiemeyerComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
William S YorkComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
Rene RanzingerComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.

Funding

TR&D1: Stem Cell and Induced Pluripotent Stem Cell Resources (Pages 116-134)P41GM103490 · NIGMS · UNIVERSITY OF GEORGIA · PI PIERCE, J. MICHAEL · 2012 to 2018
$13.7M
National Institute of General Medical Sciences P41 GM103490NIGMS NIH HHS P41 GM103490
6 · The paper itself

Abstract

Mass spectrometry (MS) is one of the most effective techniques for high-throughput, high-resolution characterization of glycan structures. Although many software applications have been developed over the last decades for the interpretation of MS data of glycan structures, only a few are capable of dealing with the large data sets produced by glycomics analysis. Furthermore, these applications utilize databases that can lead to redundant glycan annotations and do not support post-processing of the data within the software or by third party applications. To address the needs, we present GRITS Toolbox, a freely-available, platform-independent software application capable of storing and processing glycomics MS data along with associated metadata. GRITS Toolbox automatically annotates MS data using an integrated glycan identification module that references manually curated databases of mammalian glycans (provided with the software) or any user-defined databases. Extensive display routines are provided to post-process the data and refine the automated annotation using expert knowledge of the user. The software also allows side by side comparison of annotations from different MS runs or samples and exporting of annotations into Excel format.

Indexed as

Mass SpectrometrySoftwareDatabases, FactualGlycomicsfree softwareglycomicsglycomics mass spectrometric datamass spectrometry annotationmass spectrometry data processing

Identifiers

PMID30913289
PMCPMC6521942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.