Evidence map›Paper›PMID 30912957›Full record

Trial reportThe British journal of radiology2019

Stereotactic body radiotherapy to the prostate and pelvic lymph nodes: A detailed dosimetric analysis of a phase II prospective trial.

Amar U Kishan, Marguerite Tyran, Julius Weng, Shrinivasa Upadhyaya, James Lamb, Michael Steinberg, Christopher King, Minsong Cao

Abstract readClinical Trial, Phase II
In one paragraph

Trial report in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. SABR for High-Risk Prostate Cancer: A Prospective Multilevel MRI-Based Dose Escalation Trial.International journal of radiation oncology, biology, physics · 2022
    Trial
  3. Article
  4. Maintaining consistent bladder filling during external beam radiotherapy for prostate cancer.Technical innovations & patient support in radiation oncology · 2021
    Article
  5. Ultrahypofractionation of localized prostate cancer : Statement from the DEGRO working group prostate cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Review
  6. MR-Guided Radiotherapy for Prostate Cancer.Frontiers in oncology · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amar U Kishan1 Department of Radiation Oncology, University of California , Los Angeles , USA.
Marguerite Tyran1 Department of Radiation Oncology, University of California , Los Angeles , USA.
Julius Weng1 Department of Radiation Oncology, University of California , Los Angeles , USA.
Shrinivasa Upadhyaya4 Department of Biological and Agricultural Engineering, University of California , Davis , USA.
James Lamb1 Department of Radiation Oncology, University of California , Los Angeles , USA.
Michael Steinberg1 Department of Radiation Oncology, University of California , Los Angeles , USA.
Christopher King1 Department of Radiation Oncology, University of California , Los Angeles , USA.
Minsong Cao1 Department of Radiation Oncology, University of California , Los Angeles , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the dosimetric ramifications of simultaneously irradiating the prostate and pelvic lymph nodes (PLNs) with a stereotactic body radiotherapy approach based on rigid registration to intraprostatic markers (IPMs). METHODS AND MATERIALS: Nineteen patients received concurrent SBRT to the prostate and PLNs on a phase II clinical trial. The translational and rotation shifts required for rigid registration to bony anatomy and changes in bladder and rectal anatomy were compared between patients with > 90% and < 90% coverage of the nodal clinical target volume (CTV

resultsThe average V

conclusionWhile simultaneous SBRT to the prostate and PLNs based on rigid registration to IPMs provides adequate PLN coverage in most instances, overall coverage may be lower than anticipated if anatomy is unstable. Careful evaluation of bladder filling on kV-CBCT before treatment may be the most practical method for estimating accuracy prior to treatment. ADVANCES IN KNOWLEDGE: Simultaneous SBRT to the prostate and PLNs based on rigid registration to IPMs provides adequate PLN coverage in most instances.

Indexed as

Radiotherapy DosageFollow-Up StudiesHumansLymph NodesMalePelvisProspective StudiesProstateProstatic NeoplasmsRadiometryRadiosurgery

Identifiers

PMID30912957
PMCPMC6636273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.