Evidence map›Paper›PMID 30912956›Full record

ArticleThe British journal of radiology2019

Reduced motion and improved rectal dosimetry through endorectal immobilization for prostate stereotactic body radiotherapy.

Jeremiah de Leon, Michael G Jameson, David Rivest-Henault, Sarah Keats, Robba Rai, Sankar Arumugam, Lee Wilton, Diana Ngo, Gary Liney, Daniel Moses and 3 more

Open access · bronzeAbstract readEvaluation StudyMulticenter Study
In one paragraph

Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Effectiveness of rectal displacement devices in managing prostate motion: a systematic review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Pooled it
  2. Article
  3. Review
  4. Rectal retractor in prostate radiotherapy: pros and cons.Radiation oncology (London, England) · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Clinical effects of rectal retractor application in prostate cancer radiotherapy.Medical journal of the Islamic Republic of Iran · 2021
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Jeremiah de Leon1 Illawara Cancer Care Centre , Wollongong , Australia.
Michael G Jameson2 Liverpool Cancer Therapy Centre , Liverpool , Australia.
David Rivest-Henault5 Australian e-Health Research Centre, CSIRO , Herston , Australia.
Sarah Keats2 Liverpool Cancer Therapy Centre , Liverpool , Australia.
Robba Rai2 Liverpool Cancer Therapy Centre , Liverpool , Australia.
Sankar Arumugam2 Liverpool Cancer Therapy Centre , Liverpool , Australia.
Lee Wilton6 Calvary Mater Newcastle , Newcastle , Australia.
Diana Ngo2 Liverpool Cancer Therapy Centre , Liverpool , Australia.
Gary Liney2 Liverpool Cancer Therapy Centre , Liverpool , Australia.
Daniel Moses4 Faculty of Medicine, University of New South Wales , Australia.
Jason Dowling5 Australian e-Health Research Centre, CSIRO , Herston , Australia.
Jarad Martin6 Calvary Mater Newcastle , Newcastle , Australia.
Mark Sidhom2 Liverpool Cancer Therapy Centre , Liverpool , Australia.
Liverpool Hospital · AUAustralian e-Health Research Centre · AUCalvary Mater Newcastle Hospital · AUUniversity of Newcastle Australia · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePROMETHEUS (ACTRN12615000223538) is a multicentre clinical trial investigating the feasibility of 19 Gy in 2 fractions of stereotactic body radiotherapy (SBRT) as a boost technique for prostate cancer. The objective of this substudy was to evaluate intrafraction motion using cine MRI and assess the dosimetric impact of using a rectal displacement device (RDD).

methodsThe initial 10 patients recruited underwent planning CT and MRI, with and without a RDD. Cine MRI images were captured using an interleaved T2 HASTE sequence in sagittal and axial planes with a temporal resolution of 5.2 s acquired over 4.3 min. Points of interest (POIs) were defined and a validated tracking algorithm measured displacement of these points over the 4.3 min in the anteroposterior, superior-inferior and left-right directions. Plans were generated with and without a RDD to examine the impact on dosimetry.

resultsThere was an overall trend for increasing displacement in all directions as time progressed when no RDD was

conclusionThe RDD used in stereotactic prostate radiotherapy leads to reduced intrafraction motion of the prostate and rectum, with increasing improvement with time. It also results in significant improvement in rectal wall dosimetry. ADVANCES IN KNOWLEDGE: It was found that the rectal displacement device improved prostate stabilization significantly, improved rectum stabilization and dosimetry significantly. The rectal displacement device did not improve target volume dosimetry.

Indexed as

Anatomic LandmarksFeasibility StudiesHumansImmobilizationMagnetic Resonance Imaging, CineMaleMovementProstatic NeoplasmsRadiometryRadiosurgeryRadiotherapy Dosage

Identifiers

PMID30912956
PMCPMC6592081
OpenAlexW2922688802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.