Evidence map›Paper›PMID 30912837›Full record

ArticleJAMA2019

Association Between Year of Birth and 1-Year Survival Among Extremely Preterm Infants in Sweden During 2004-2007 and 2014-2016.

Mikael Norman, Boubou Hallberg, Thomas Abrahamsson, Lars J Björklund, Magnus Domellöf, Aijaz Farooqi, Cathrine Foyn Bruun, Christian Gadsbøll, Lena Hellström-Westas, Fredrik Ingemansson and 9 more

Erratum issuedAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in JAMA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 159 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
159citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

159 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Singapore Neonatal Resuscitation Guidelines 2026.Singapore medical journal · 2026
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  11. Neurodevelopmental outcomes at age 3 years of preterm infants born at 22-31 weeks' gestation.Journal of perinatology : official journal of the California Perinatal Association · 2025
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  16. Effects ofCell reports. Medicine · 2021
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  19. The role of prophylactic arginine supplementation for prevention of bronchopulmonary dysplasia in extremely preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
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99 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Mikael NormanDivision of Pediatrics, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden.
Boubou HallbergDivision of Pediatrics, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden.
Thomas AbrahamssonDepartments of Clinical and Experimental Medicine and Pediatrics, Linköping University, Linköping, Sweden.
Lars J BjörklundDepartments of Clinical Sciences and Pediatrics, Lund University and Skåne University Hospital, Lund, Sweden.
Magnus DomellöfDepartments of Clinical Sciences and Pediatrics, Umeå University, Umeå Sweden.
Aijaz FarooqiDepartments of Clinical Sciences and Pediatrics, Umeå University, Umeå Sweden.
Cathrine Foyn BruunDepartments of Clinical Sciences and Pediatrics, Umeå University, Umeå Sweden.
Christian GadsbøllDepartments of Clinical and Experimental Medicine and Pediatrics, Linköping University, Linköping, Sweden.
Lena Hellström-WestasDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Fredrik IngemanssonDepartment of Pediatrics, Ryhov County Hospital, Jönköping County Council, Jonkoping, Sweden.
Karin KällénCentre for Reproductive Epidemiology, Lund University, Lund, Sweden.
David LeyDepartments of Clinical Sciences and Pediatrics, Lund University and Skåne University Hospital, Lund, Sweden.
Karel MaršálDepartments of Clinical Sciences and Obstetrics and Gynecology, Lund University, Skåne University Hospital, Lund, Sweden.
Erik NormannDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Fredrik SereniusDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Olof StephanssonDivision of Clinical Epidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Lennart StigsonDepartment of Pediatrics, Institute for Clinical Sciences, Queen Silvia Children's Hospital, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.
Petra Um-BergströmDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Stellan HåkanssonSwedish Neonatal Quality Register, Umeå University Hospital, Umeå, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Since 2004-2007, national guidelines and recommendations have been developed for the management of extremely preterm births in Sweden. If and how more uniform management has affected infant survival is unknown. Objective: To compare survival of extremely preterm infants born during 2004-2007 with survival of infants born during 2014-2016. Design, Setting and Participants: All births at 22-26 weeks' gestational age (n = 2205) between April 1, 2004, and March 31, 2007, and between January 1, 2014, and December 31, 2016, in Sweden were studied. Prospective data collection was used during 2004-2007. Data were obtained from the Swedish pregnancy, medical birth, and neonatal quality registries during 2014-2016. Exposures: Delivery at 22-26 weeks' gestational age. Main Outcomes and Measures: The primary outcome was infant survival to the age of 1 year. The secondary outcome was 1-year survival among live-born infants who did not have any major neonatal morbidity (specifically, without intraventricular hemorrhage grade 3-4, cystic periventricular leukomalacia, necrotizing enterocolitis, retinopathy of prematurity stage 3-5, or severe bronchopulmonary dysplasia). Results: During 2004-2007, 1009 births (3.3/1000 of all births) occurred at 22-26 weeks' gestational age compared with 1196 births (3.4/1000 of all births) during 2014-2016 (P = .61). One-year survival among live-born infants at 22-26 weeks' gestational age was significantly lower during 2004-2007 (497 of 705 infants [70%]) than during 2014-2016 (711 of 923 infants [77%]) (difference, -7% [95% CI, -11% to -2.2%], P = .003). One-year survival among live-born infants at 22-26 weeks' gestational age and without any major neonatal morbidity was significantly lower during 2004-2007 (226 of 705 infants [32%]) than during 2014-2016 (355 of 923 infants [38%]) (difference, -6% [95% CI, -11% to -1.7%], P = .008). Conclusions and Relevance: Among live births at 22-26 weeks' gestational age in Sweden, 1-year survival improved between 2004-2007 and 2014-2016.

Indexed as

Infant, Extremely PrematureDevelopmental DisabilitiesFemaleFetal ViabilityGestational AgeHumansInfantInfant MortalityInfant, NewbornInfant, Premature, DiseasesIntensive Care, NeonatalMaleProspective StudiesStillbirthSurvival RateSweden

Identifiers

PMID30912837
PMCPMC6439685

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.