Evidence map›Paper›PMID 30912327›Full record

ArticleAllergy, asthma & immunology research2019

Evaluation of Neutrophil Activation Status According to the Phenotypes of Adult Asthma.

Seung Hyun Kim, Udval Uuganbayar, Hoang Kim Tu Trinh, Duy Le Pham, Namhyo Kim, Minji Kim, Hyeukjun Sohn, Hae Sim Park

Open access · hybridAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

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  14. The role of neutrophils in asthma.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Seung Hyun KimTranslational Research Laboratory for Inflammatory Disease, Clinical Trial Center, Ajou University Medical Center, Suwon, Korea. kimsh@ajou.ac.kr.ORCID https://orcid.org/0000-0003-1789-8964
Udval UuganbayarDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
Hoang Kim Tu TrinhDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-2598-788X
Duy Le PhamDepartment of Immunology, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.
Namhyo KimDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
Minji KimDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
Hyeukjun SohnDepartment of Biomedical Science, Ajou University School of Medicine, Suwon, Korea.
Hae Sim ParkDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea. hspark@ajou.ac.kr.ORCID https://orcid.org/0000-0003-2614-0303
Ajou University · KRUniversity of Medicine and Pharmacy at Ho Chi Minh City · VN

Funding

Ministry of Science, ICT and Future Planning 2015R1C1A2A01053492Ministry of Science, ICT and Future Planning 2018R1A2B6004905
6 · The paper itself

Abstract

purposeNeutrophils are considered key effector cells in the pathogenic mechanisms of airway inflammation in asthma. This study assessed the activation status of neutrophils in adult asthmatics, and the therapeutic potential of FTY720, a synthetic sphingosine-1-phosphate analog, on activated neutrophils using an

methodsWe isolated peripheral blood neutrophils (PBNs) from 59 asthmatic patients (including 20 aspirin-exacerbated respiratory disease [AERD] and 39 aspirin-tolerant asthma [ATA] groups). PBNs were stimulated with

results

conclusionsOur findings suggest a useful

Indexed as

asthmaFTY720Neutrophilsreactive oxygen species

Identifiers

PMID30912327
PMCPMC6439190
OpenAlexW2942228747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.