Evidence map›Paper›PMID 30912324›Full record

ArticleAllergy, asthma & immunology research2019

Trabecular Bone Score Is More Sensitive to Asthma Severity and Glucocorticoid Treatment Than Bone Mineral Density in Asthmatics.

Yong Jun Choi, Hyun Young Lee, Dukyong Yoon, Anhye Kim, Yoo Seob Shin, Hae Sim Park, Young Min Ye

Open access · hybridAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Update on trabecular bone score.Archives of endocrinology and metabolism · 2022
    Review
  5. The association of asthma and its subgroups with osteoporosis: a cross-sectional study using KoGES HEXA data.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020
    Article
  6. Future Risks in Patients With Severe Asthma.Allergy, asthma & immunology research · 2019
    Review
  7. Article
  8. Glucocorticoids and Trabecular Bone Score.Journal of medicine and life
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yong Jun ChoiDepartment of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0003-3960-8470
Hyun Young LeeClinical Trial Center, Ajou University Medical Center, Suwon, Korea.
Dukyong YoonDepartment of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0003-1635-8376
Anhye KimClinical Trial Center, Ajou University Medical Center, Suwon, Korea.ORCID https://orcid.org/0000-0002-6622-8089
Yoo Seob ShinDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-9855-3185
Hae Sim ParkDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0003-2614-0303
Young Min YeDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea. ye9007@ajou.ac.kr.ORCID https://orcid.org/0000-0002-7517-1715
Ajou University · KR

Funding

Ministry of Health and Welfare HI17C0970
6 · The paper itself

Abstract

purposeIn asthmatic patients, treatment with corticosteroids, in addition to conventional risk factors for osteoporosis, may lead to bone loss. Trabecular bone score (TBS) is an indirect new parameter of bone quality. This study aimed to evaluate TBS in asthmatics in comparison to propensity score-matched controls and to investigate correlations between TBS and cumulative systemic and inhaled corticosteroid doses 1 year prior to bone mineral density (BMD) measurement in patients with asthma.

methodsIn total, 627 patients with asthma and the same number of non-asthmatic controls matched for sex and age were included in this retrospective cohort study. TBS was calculated in the lumbar region, based on 2 dimensional projections of dual-energy X-ray absorptiometry.

resultsPatients with severe asthma exhibited lower vertebral TBS values (1.32 ± 0.1) than those with non-severe asthma (1.36 ± 0.1,

conclusionsTBS can be used as an early indicator of altered bone quality stemming from glucocorticoid therapy or, possibly, more severe asthma.

Indexed as

Asthmabone mineral densitytrabecular bone score

Identifiers

PMID30912324
PMCPMC6439196
OpenAlexW2913954394

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.