Evidence map›Paper›PMID 30911838›Full record

ArticleInternational journal of legal medicine2020

Evaluating the effects of causes of death on postmortem interval estimation by ATR-FTIR spectroscopy.

Kai Zhang, Qi Wang, Ruina Liu, Xin Wei, Zhouru Li, Shuanliang Fan, Zhenyuan Wang

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Article in International journal of legal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Development of Forensically ImportantAnimals : an open access journal from MDPI · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kai ZhangDepartment of Forensic Pathology, College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China.
Qi WangDepartment of Forensic Medicine, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Ruina LiuDepartment of Forensic Pathology, College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China.
Xin WeiDepartment of Forensic Pathology, College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China.
Zhouru LiDepartment of Forensic Medicine, Xuzhou Medical University, Xuzhou, 221004, People's Republic of China.
Shuanliang FanDepartment of Forensic Pathology, College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China. xafansl@mail.xjtu.edu.cn.
Zhenyuan WangDepartment of Forensic Pathology, College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China. wzy218@xjtu.edu.cn.

Funding

National Natural Science Foundation of China 81730056
6 · The paper itself

Abstract

Estimating postmortem interval (PMI) is one of the most challenging tasks in forensic practice due to the effects of many factors. Here, attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy combined with chemometrics was utilized to evaluate the effects of causes of death when estimating PMI and to establish a partial least square (PLS) regression model, which can precisely predict PMI under different causes of death. First, the sensitivities to causes of death (brainstem injury, mechanical asphyxia, and hemorrhage shock) of seven kinds of organs were evaluated based on their degrees of cohesion and separation. Then, the liver was selected as the most sensitive organ to establish a PMI estimation model to compare the predicted deviations from different causes of death. It turns out that the cause of death has no significant effect on estimating PMI. Next, a PLS regression model was built with kidney tissues, which have the lowest sensitivity, and this model showed a satisfactory predictive ability and wide applicability. This study demonstrates the feasibility of using ATR-FTIR spectroscopy in conjunction with chemometrics as a powerful alternative for detecting changes in biochemistry and estimating PMI. A new perspective was also provided for evaluating the effect of causes of death when predicting PMI.

Indexed as

Cause of DeathPostmortem ChangesSpectroscopy, Fourier Transform InfraredAnimalsBiomarkersKidneyLeast-Squares AnalysisLiverMaleModels, AnimalRatsRats, Sprague-DawleySensitivity and SpecificityBiomarkersCause of deathChemometricsFTIR spectroscopyPartial least-squaresPostmortem interval

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.