Evidence map›Paper›PMID 30911807›Full record

ReviewIntensive care medicine2019

Diagnostic and therapeutic approach to infectious diseases in solid organ transplant recipients.

Jean-François Timsit, Romain Sonneville, Andre C Kalil, Matteo Bassetti, Ricard Ferrer, Samir Jaber, Fanny Lanternier, Charles-Edouard Luyt, Flavia Machado, Malgorzata Mikulska and 7 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Intensive care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.

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  18. Assessment ofInternational journal of molecular sciences · 2025
    Article
  19. Serological Profile of Anti-Tropical medicine and infectious disease · 2025
    Article
  20. Successful Treatment of OXA-23Infection and drug resistance · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 6 countries.

Jean-François TimsitMedical and Infectious Diseases ICU (MI2), APHP Bichat University Hospital, 75018, Paris, France. Jean-francois.timsit@aphp.fr.ORCID 0000-0002-6063-7383
Romain SonnevilleMedical and Infectious Diseases Intensive Care Unit, AP-HP, Bichat-Claude Bernard University Hospital, Paris Diderot University, Paris, France.
Andre C KalilTransplant Infectious Diseases Program, University of Nebraska Medical Center, 98500 Nebraska Medical Center, Omaha, NE, 68198, USA.
Matteo BassettiInfectious Diseases Clinic, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Integrata, Udine, Italy.
Ricard FerrerDepartment of Intensive Care, Shock, Organ Dysfunction and Resuscitation Research Group (SODIR-VHIR), Vall D'Hebron University Hospital, Barcelona, Spain.
Samir JaberAnaesthesia and Critical Care Department, Saint Eloi Teaching Hospital, PhyMedExp University of Montpellier, 34295, Montpellier, France.
Fanny LanternierService de Maladies Infectieuses et Tropicales, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris (APHP), Université Paris Descartes, Paris, France.
Charles-Edouard LuytMédecine Intensive Réanimation, Cardiology Institute, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Flavia MachadoAnesthesiology, Pain and Intensive Care Department, Federal University of São Paulo, São Paulo, Brazil.
Malgorzata MikulskaDivision of Infectious Diseases, University of Genova (DISSAL) and Ospedale Polyclinico San Martino, Genova, Italy.
Laurent PapazianService de Médecine Intensive-Réanimation, Hôpital Nord-AP-HM, Aix-Marseille Université, Marseille, France.
Fréderic PèneService de Médecine Intensive-Réanimation, Hôpital Cochin, Hôpitaux Universitaires Paris-Centre, Assistance Publique-Hôpitaux de Paris, Paris, France.
Garyphalia Poulakou3rd Department of Medicine, School of Medicine, Sotiria General Hospital of Athens, Athens National and Kapodistrian University, 152 Mesogion St, 11527, Athens, Greece.
Claudio ViscoliDivision of Infectious Diseases, University of Genova (DISSAL) and Ospedale Polyclinico San Martino, Genova, Italy.
Michel WolffService de Réanimation Neurochirurgicale, Hôpital Sainte-Anne, GHU Paris Psychiatrie & Neurosciences, 1, Rue Cabanis, 75014, Paris, France.
Lara ZafraniMedical ICU, Saint-Louis Hospital, AP-HP, INSERM U976, Paris Diderot University, Paris, France.
Christian Van DeldenTransplant Infectious Diseases Unit, University Hospitals Geneva, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, Switzerland.
Inserm · FROspedale Policlinico San Martino · ITAix-Marseille Université · FRCentre Hospitalier Sainte-Anne · FRCentre National de la Recherche Scientifique · FRHôpital Necker-Enfants Malades · FRSotiria General Hospital · GRUniversidade Federal de São Paulo · BRUniversité Claude Bernard Lyon 1 · FRUniversité de Montpellier · FRUniversity Hospital of Geneva · CHUniversity of Nebraska Medical Center · USUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrognosis of solid organ transplant (SOT) recipients has improved, mainly because of better prevention of rejection by immunosuppressive therapies. However, SOT recipients are highly susceptible to conventional and opportunistic infections, which represent a major cause of morbidity, graft dysfunction and mortality.

methodsNarrative review.

resultsWe cover the current epidemiology and main aspects of infections in SOT recipients including risk factors such as postoperative risks and specific risks for different transplant recipients, key points on anti-infective prophylaxis as well as diagnostic and therapeutic approaches. We provide an up-to-date guide for management of the main syndromes that can be encountered in SOT recipients including acute respiratory failure, sepsis or septic shock, and central nervous system infections as well as bacterial infections with multidrug-resistant strains, invasive fungal diseases, viral infections and less common pathogens that may impact this patient population.

conclusionWe provide state-of the art review of available knowledge of critically ill SOT patients with infections.

Indexed as

Anti-Bacterial AgentsCommunicable DiseasesHumansImmunocompromised HostOrgan TransplantationTransplant RecipientsAnti-Bacterial AgentsImmunocompromizedOutcomeSepsisSeptic shockSolid organ recipient

Identifiers

PMID30911807
PMCPMC7079836
OpenAlexW2942483921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.