ArticleCommunications biology2019
Promoting healthspan and lifespan with caloric restriction in primates.
Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- Dietary restriction in aging and longevity.Nature aging · 2026Review
- Modelling the ageing dependence of cancer evolutionary trajectories.Nature reviews. Cancer · 2025Review
- Resveratrol does not mimic the positive effects of calorie restriction on lifespan in Microcebus murinus.Communications biology · 2025Article
- Short-term fasting of a single amino acid extends lifespan.GeroScience · 2024Article
- An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome.Nature communications · 2024Article
- Article
- The Beneficial Effects of Dietary Interventions on Gut Microbiota-An Up-to-Date Critical Review and Future Perspectives.Nutrients · 2023Review
- Survival rates and mortality risks of Plecturocebus cupreus at the California National Primate Research Center.American journal of primatology · 2023Article
- Metabolomics analysis of dietary restriction results in a longer lifespan due to alters of amino acid levels in larval hemolymph of Bombyx mori.Scientific reports · 2023Article
- Overweight Management through Mild Caloric Restriction in Multigenerational Long-Tailed Macaque Breeding Groups.Veterinary sciences · 2022Article
- Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice.Genetics · 2022Article
- The microbiota composition drives personalized nutrition: Gut microbes as predictive biomarkers for the success of weight loss diets.Frontiers in nutrition · 2022Review
- Parental age at conception on mouse lemur's offspring longevity: Sex-specific maternal effects.PloS one · 2022Article
- Late-life intermittent fasting decreases aging-related frailty and increases renal hydrogen sulfide production in a sexually dimorphic manner.GeroScience · 2021Article
- Diabetes Mellitus and Cardiovascular Diseases: Nutraceutical Interventions Related to Caloric Restriction.International journal of molecular sciences · 2021Review
- Transgenerational fitness effects of lifespan extension by dietary restriction inProceedings. Biological sciences · 2021Article
- The goal of geroscience is life extension.Oncotarget · 2021Article
- Immunosenescence in Childhood Cancer Survivors and in Elderly: A Comparison and Implication for Risk Stratification.Frontiers in aging · 2021Review
- Article
- Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementia.Ageing research reviews · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent data confirmed the efficiency of caloric restriction for promoting both healthspan and lifespan in primates, but also revealed potential adverse effects at the central level. This paper proposes perspectives and future directions to counterbalance potential adverse effects. Efforts should be made in combining nutrition-based clinical protocols with therapeutic and/or behavioral interventions to aim for synergetic effects, and therefore delay the onset of age-related diseases without adverse effects.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.