Evidence map›Paper›PMID 30911601›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2019

Neuropsychiatric symptoms in patients with dementia and the longitudinal costs of informal care in the Cache County population.

Gail B Rattinger, Chelsea L Sanders, Elizabeth Vernon, Sarah Schwartz, Stephanie Behrens, Constantine G Lyketsos, JoAnn T Tschanz

Abstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  12. The Neuropsychiatric Inventory: Development and Applications.Journal of geriatric psychiatry and neurology · 2020
    Review
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  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gail B RattingerSchool of Pharmacy and Pharmaceutical Sciences, Binghamton University State University of New York, New York, NY, USA.
Chelsea L SandersDepartment of Psychology, Utah State University, Logan, UT, USA.
Elizabeth VernonDepartment of Psychology, Utah State University, Logan, UT, USA.
Sarah SchwartzDepartment of Mathematics and Statistics, Utah State University, Logan, UT, USA.
Stephanie BehrensDepartment of Psychology, Utah State University, Logan, UT, USA.
Constantine G LyketsosJohns Hopkins Bayview Medical Center, Baltimore, MD, USA.
JoAnn T TschanzDepartment of Psychology, Utah State University, Logan, UT, USA.

Funding

'T V ASSESSMENT - MEMORY DISORDERED PATIENTS'P50AG005146 · NIA · JOHNS HOPKINS UNIVERSITY · PI ALBERT, MARILYN S. · 1985 to 2019
$37.6M
EPIDEMIOLOGY OF DEMENTIA IN CACHE COUNTY, UTAHR01AG011380 · NIA · JOHNS HOPKINS UNIVERSITY · PI WELSH-BOHMER, KATHLEEN ANNE · 1994 to 2009
$12.2M
Progression of Dementia: A Population StudyR01AG021136 · NIA · UTAH STATE UNIVERSITY · PI LYKETSOS, CONSTANTINE G, TSCHANZ, JOANN T · 2002 to 2010
$6.0M
NIA NIH HHS P50 AG005146NIA NIH HHS R01 AG011380NIA NIH HHS R01 AG021136
6 · The paper itself

Abstract

introductionSeverity of dementia and neuropsychiatric symptoms contribute to increasing informal care costs. We examined which neuropsychiatric symptoms subdomains (NPS-SD) were associated with informal costs in a population-based sample.

methodsDementia progression and informal costs (2015 dollars) were estimated from the Cache County Dementia Progression Study. Overall NPS and specific NPS-SD were assessed with the Neuropsychiatric Inventory. Generalized Estimating Equations (GEE with gamma-distribution/log-link) modeled the relationship between NPS-SDs and informal cost trajectories.

resultsTwo hundred eighty participants (52.1% female; age M = 85.67, SD = 5.60) exhibited an adjusted cost increase of 5.6% ( DISCUSSION: We extend our prior work on informal costs and dementia severity by identifying NPS-SD associated with informal costs. Interventions targeting NPS-SD may lower informal costs.

Indexed as

Alzheimer's diseaseDementiaInformal costs of dementiaNeuropsychiatric symptoms

Identifiers

PMID30911601
PMCPMC6416410

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.