Evidence map›Paper›PMID 30911463›Full record

ArticleLeukemia research reports2019

Myodesopsia is a symptom of central nervous system blast crisis in chronic myeloid leukemia.

Kazuyoshi Ishii, Aya Nakaya, Shinya Fujita, Atsushi Satake, Yoshiko Azuma, Yukie Tsubokura, Ryo Saito, Akiko Konishi, Masaaki Hotta, Hideaki Yoshimura and 2 more

Erratum issuedOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Kazuyoshi IshiiFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Aya NakayaFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Shinya FujitaFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Atsushi SatakeFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Yoshiko AzumaFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Yukie TsubokuraFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Ryo SaitoFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Akiko KonishiFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Masaaki HottaFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Hideaki YoshimuraFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Tomoki ItoFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Shosaku NomuraFirst Department of Internal Medicine, Kansai Medical University Medical Center, Japan.
Kansai Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 49-year-old woman diagnosed with chronic myeloid leukemia in the chronic phase was started on dasatinib treatment, after which she complained of myodesopsia. Nineteen months after diagnosis, the patient again complained of myodesopsia and developed bilateral optic neuritis. Cerebrospinal fluid analysis revealed an increase in blasts, although peripheral blood and bone marrow examination confirmed that the patient remained in a molecular response to tyrosine kinase inhibitor (TKI) therapy. The patient was diagnosed with an isolated central nervous system blast crisis, a rare occurrence with second-generation TKI therapy, and the initial presentation of myodesopsia represented a symptom of this condition.

Indexed as

Blast crisisCentral nervous systemChronic myeloid leukemiaMyodesopsiaTyrosine kinase inhibitor

Identifiers

PMID30911463
PMCPMC6416525
OpenAlexW2919498650

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.