ReviewCureus2019
Where is the Evidence? A Narrative Literature Review of the Treatment Modalities for Autism Spectrum Disorders.
Review in Cureus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- A Phase III Study of Bumetanide Oral Liquid Formulation for the Treatment of Children and Adolescents Aged Between 7 and 17 Years with Autism Spectrum Disorder (SIGN 1 Trial): Participant Baseline Characteristics.Child psychiatry and human development · 2023Trial
- The Effect of Teaching Initiations on the Communication of Children with Autism Spectrum Disorder: A Randomized Clinical Trial.Journal of autism and developmental disorders · 2022Trial
- Evaluation of sleep problems and related factors in children newly diagnosed with autism spectrum disorder.International journal of developmental disabilities · 2026Article
- Differential analysis of Short chain fatty acids incubation in autistic organoids based on transcriptome sequencing.PloS one · 2026Article
- Experiences of Autistic Individuals, Caregivers and Healthcare Providers with ABA-Derived Therapies: a Sequential Exploratory Mixed Methods Study.Journal of autism and developmental disorders · 2025Article
- Multi-level treatment outcome evaluation in adolescents with autism spectrum disorder.Child and adolescent psychiatry and mental health · 2025Article
- Optical genome mapping reveals novel structural variations in an autism spectrum disorder cohort.Computational and structural biotechnology journal · 2025Article
- Gene therapy as an emerging treatment forFundamental research · 2024Review
- Article
- Pilot Study of Personalized Transcranial Magnetic Stimulation with Spectral Electroencephalogram Analyses for Assessing and Treating Persons with Autism.Journal of personalized medicine · 2024Article
- TheThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Development and validation of the social-emotional rating scale for autism spectrum disorder (SERA) in an Indian sample.International journal of developmental disabilities · 2024Article
- Registered Behavior Technicians' Training Experiences for Severe Problem Behavior: A Survey.Behavior analysis in practice · 2023Article
- Multimodal Physiotherapy Approach for Autism With Speech Impairment and Attention Deficit: A Case Report.Cureus · 2023Article
- Why We Need a Developmentally Appropriate Trauma Diagnosis for Children: a 10-Year Update on Developmental Trauma Disorder.Journal of child & adolescent trauma · 2023Article
- Canagliflozin Ameliorates Oxidative Stress and Autistic-like Features in Valproic-Acid-Induced Autism in Rats: Comparison with Aripiprazole Action.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Urban-Rural Disparity in the Incidence of Diagnosed Autism Spectrum Disorder in Taiwan: A 10-Year National Birth Cohort Follow-up Study.Journal of autism and developmental disorders · 2023Article
- Applied behavioral analysis for the skill performance of children with autism spectrum disorder.Frontiers in psychiatry · 2023Article
- Torasemide Improves the Propionic Acid-Induced Autism in Rats: A Histopathological and Imaging Study.Alpha psychiatry · 2023Article
- Repurposing SGLT2 Inhibitors for Neurological Disorders: A Focus on the Autism Spectrum Disorder.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most important thing about autism spectrum disorder (ASD) is that there is, in fact, no cure for this disorder; however, currently, there are many claims of pharmacological and dietary therapies and behavioral interventions that are said to improve outcome or even lead to "cure" or "recovery." It continues to remain a challenging condition for children and their families. Research conducted on many of these treatment modalities is limited and, consequently, sufficient evidence does not exist to support their use. The primary aim of this paper was to search for the evidence of the efficacy of each treatment for autism till now. We reviewed different treatment modalities and randomized clinical trials on each treatment to look for the evidence. Although there are interventions that may be effective in alleviating some symptoms and improving skills that help autistic persons lead more productive lives, proven benefits were observed only with applied behavioral analysis (ABA) and some psychopharmacologic agents.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.