Evidence map›Paper›PMID 30911434›Full record

ArticleAmerican journal of nuclear medicine and molecular imaging2019

Diagnostic HER2-binding radiopharmaceutical, [

Irina Velikyan, Philip Schweighöfer, Joachim Feldwisch, Johanna Seemann, Fredrik Y Frejd, Henrik Lindman, Jens Sörensen

Registry-linked trialAbstract read
In one paragraph

Article in American journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05619016 (Phase II Study of [68Ga]Ga-ABY-025 PET for Non-invasive Quantification of HER2-status in Solid Tumors), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05619016 phase2unknown statusnot on this mapstarted 2022, after this paper: background citation

Phase II Study of [68Ga]Ga-ABY-025 PET for Non-invasive Quantification of HER2-status in Solid Tumors

TypeinterventionalSponsorKarolinska University HospitalRan2022 to 2025Enrolled72ConditionsEsophageal Neoplasms, Gastric Neoplasms Malignant, Breast Cancer, HER2-positive Gastric CancerArms[68Ga]Ga-ABY-025 PET, Biopsy and analysis of HER2 expression
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Human Epidermal Growth Factor Receptor 2-Targeting [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Trial
  4. Review
  5. Article
  6. Review
  7. Towards Optimal AutomatedJournal of labelled compounds & radiopharmaceuticals · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Bacterial Cell Display for Selection of Affibody Molecules.Methods in molecular biology (Clifton, N.J.) · 2023
    Review
  12. Theranostics in breast cancer.Frontiers in nuclear medicine · 2023
    Review
  13. Co-injection of anti-HER2 antibody Trastuzumab does not increase efficacy of [American journal of nuclear medicine and molecular imaging · 2023
    Article
  14. Advances in aptamer-based nuclear imaging.European journal of nuclear medicine and molecular imaging · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Synthesis of a novelEJNMMI research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Irina VelikyanSection of Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University Uppsala, Sweden.
Philip SchweighöferEckert and Ziegler Eurotope GmbH Berlin, Germany.
Joachim FeldwischAffibody AB Solna, Sweden.
Johanna SeemannEckert and Ziegler Eurotope GmbH Berlin, Germany.
Fredrik Y FrejdAffibody AB Solna, Sweden.
Henrik LindmanDepartment of Immunology, Genetics and Pathology Uppsala, Sweden.
Jens SörensenSection of Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University Uppsala, Sweden.
Uppsala University · SEEckert & Ziegler (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[

Indexed as

Affibodybreast cancerclinical studygallium-68GMPHER2

Identifiers

PMID30911434
PMCPMC6420710
OpenAlexW2980636753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.